Dual effects of serum urate on stroke risk and prognosis: insights from Mendelian randomization

Dual effects of serum urate on stroke risk and prognosis: insights from Mendelian randomization

BackgroundTo investigate the causal associations of serum urate (SUA) with stroke risk and prognosis using Mendelian randomization (MR) and the potential mediating role of stroke risk factors in the causal pathways.MethodsWe used the random-effects inverse variance weighting (IVW) as our primary met...

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Bibliographic Details
Main Authors: Shixuan Chen, Zhenzhen Chen, Qingqing Xu, Xia Jiang, Chuyong Lin, Jing Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Neurology
Subjects:
uric acid
stroke
blood pressure
genetic instrumental variables
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1359292/full

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