Protocol for electrophysiological measurements of circadian changes in excitability in dentate granule cells from adult mice

Summary: Many types of neurons exhibit a daily rhythm of intrinsic excitability. Here, we present a protocol for assessing circadian regulation of dentate granule cell excitability using a mouse model for conditional knockout of the molecular clock protein BMAL1. We describe steps for obtaining heal...

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Bibliographic Details
Main Authors: Jose Carlos Gonzalez, Haeun Lee, Linda Overstreet-Wadiche
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724004209

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