Netrin-1 reduces lung ischemia-reperfusion injury by increasing the proportion of regulatory T cells

Objective Inflammation is the primary mechanism of lung ischemia-reperfusion injury (LIRI) and neurologic factors can regulate inflammatory immune responses. Netrin-1 is an axonal guidance molecule, but whether Netrin-1 plays a role in LIRI remains unclear. Methods A mouse model of LIRI was establis...

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Bibliographic Details
Main Authors: Zhili Chen, Yuxi Chen, Jue Zhou, Yong Li, Changyao Gong, Xiaobo Wang
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520926415