Thymoma With Pancytopenia: A Case Report and Review of The Literature

Although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. We only found one case in literature reviews.We report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. With a...

Full description

Bibliographic Details
Main Authors: A. Alavi, T. Fakheri, S. Hoda, H. Amani, M. Aghajanzadeh, F. Moghadam Manesh
Format: Article
Language:English
Published: Iran University of Medical Sciences 2007-08-01
Series:Medical Journal of The Islamic Republic of Iran
Subjects:
Online Access:http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-172&slc_lang=en&sid=1
_version_ 1818291130971717632
author A. Alavi
T. Fakheri
S. Hoda
H. Amani
M. Aghajanzadeh
F. Moghadam Manesh
author_facet A. Alavi
T. Fakheri
S. Hoda
H. Amani
M. Aghajanzadeh
F. Moghadam Manesh
author_sort A. Alavi
collection DOAJ
description Although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. We only found one case in literature reviews.We report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. With a mediastinotomy incision, biopsy of the tumor was obtained.The report of the pathologist was thymoma of predominant epithelial type. After a median sternotomy, there was complete resection of the tumor with removal of two segments of the right upper lobe and the involved pericardium (stage 3 of Thymoma). Unfortunately, after complete resection of the tumor there was no improvement in the pancytopenia. The patient died because of sepsis about 33 days after operation.
first_indexed 2024-12-13T02:39:11Z
format Article
id doaj.art-6a1cf602c0f94cb5b75a68008e10457f
institution Directory Open Access Journal
issn 1016-1430
2251-6840
language English
last_indexed 2024-12-13T02:39:11Z
publishDate 2007-08-01
publisher Iran University of Medical Sciences
record_format Article
series Medical Journal of The Islamic Republic of Iran
spelling doaj.art-6a1cf602c0f94cb5b75a68008e10457f2022-12-22T00:02:20ZengIran University of Medical SciencesMedical Journal of The Islamic Republic of Iran1016-14302251-68402007-08-01212115118Thymoma With Pancytopenia: A Case Report and Review of The LiteratureA. AlaviT. FakheriS. HodaH. AmaniM. AghajanzadehF. Moghadam ManeshAlthough the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. We only found one case in literature reviews.We report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. With a mediastinotomy incision, biopsy of the tumor was obtained.The report of the pathologist was thymoma of predominant epithelial type. After a median sternotomy, there was complete resection of the tumor with removal of two segments of the right upper lobe and the involved pericardium (stage 3 of Thymoma). Unfortunately, after complete resection of the tumor there was no improvement in the pancytopenia. The patient died because of sepsis about 33 days after operation.http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-172&slc_lang=en&sid=1ThymomaPancytopeniaRed-Cell AplasiaThymectomy
spellingShingle A. Alavi
T. Fakheri
S. Hoda
H. Amani
M. Aghajanzadeh
F. Moghadam Manesh
Thymoma With Pancytopenia: A Case Report and Review of The Literature
Medical Journal of The Islamic Republic of Iran
Thymoma
Pancytopenia
Red-Cell Aplasia
Thymectomy
title Thymoma With Pancytopenia: A Case Report and Review of The Literature
title_full Thymoma With Pancytopenia: A Case Report and Review of The Literature
title_fullStr Thymoma With Pancytopenia: A Case Report and Review of The Literature
title_full_unstemmed Thymoma With Pancytopenia: A Case Report and Review of The Literature
title_short Thymoma With Pancytopenia: A Case Report and Review of The Literature
title_sort thymoma with pancytopenia a case report and review of the literature
topic Thymoma
Pancytopenia
Red-Cell Aplasia
Thymectomy
url http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-172&slc_lang=en&sid=1
work_keys_str_mv AT aalavi thymomawithpancytopeniaacasereportandreviewoftheliterature
AT tfakheri thymomawithpancytopeniaacasereportandreviewoftheliterature
AT shoda thymomawithpancytopeniaacasereportandreviewoftheliterature
AT hamani thymomawithpancytopeniaacasereportandreviewoftheliterature
AT maghajanzadeh thymomawithpancytopeniaacasereportandreviewoftheliterature
AT fmoghadammanesh thymomawithpancytopeniaacasereportandreviewoftheliterature