Transplantation of Predegenerated Peripheral Nerves after Complete Spinal Cord Transection in Rats: Effect of Neural Precursor Cells and Pharmacological Treatment with the Sulfoglycolipid Tol-51

Transplantation of Predegenerated Peripheral Nerves after Complete Spinal Cord Transection in Rats: Effect of Neural Precursor Cells and Pharmacological Treatment with the Sulfoglycolipid Tol-51

Following spinal cord injury (SCI), the regenerative capacity of the central nervous system (CNS) is severely limited by the failure of axonal regeneration. The regeneration of CNS axons has been shown to occur by grafting predegenerated peripheral nerves (PPNs) and to be promoted by the transplanta...

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Bibliographic Details
Main Authors: Alejandro Arriero-Cabañero, Elisa García-Vences, Stephanie Sánchez-Torres, Sergio Aristizabal-Hernandez, Concepción García-Rama, Enrique Pérez-Rizo, Alfonso Fernández-Mayoralas, Israel Grijalva, Vinnitsa Buzoianu-Anguiano, Ernesto Doncel-Pérez, Jörg Mey
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Cells
Subjects:
traumatic spinal cord injury
predegenerated peripheral nerve
neural precursor cells
Tol-51
axonal regeneration
modified BBB scale
Online Access:https://www.mdpi.com/2073-4409/13/16/1324

Internet

https://www.mdpi.com/2073-4409/13/16/1324

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