Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery
In Brazil, 1 million burn accidents occur annually, and subsequent wound infections account for 75% cases of deaths among these patients, in addition to inducing deformities in the affected areas. Therefore, the aim of this study was to discuss the current status of mesenchymal stem cells, with an e...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Cirurgia Plástica
2016-09-01
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| Series: | Revista Brasileira de Cirurgia Plástica |
| Subjects: | |
| Online Access: | http://www.rbcp.org.br/export-pdf/1773/en_v31n3a20.pdf |
| _version_ | 1797416442032816128 |
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| author | Charlene Silvestrin Celi Garcia Luiz Carlos Celi Garcia João Antonio Pêgas Henriques Mariana Roesch Ely Paulo Miguel Celi Garcia |
| author_facet | Charlene Silvestrin Celi Garcia Luiz Carlos Celi Garcia João Antonio Pêgas Henriques Mariana Roesch Ely Paulo Miguel Celi Garcia |
| author_sort | Charlene Silvestrin Celi Garcia |
| collection | DOAJ |
| description | In Brazil, 1 million burn accidents occur annually, and subsequent wound infections account for 75% cases of deaths among these patients, in addition to inducing deformities in the affected areas. Therefore, the aim of this study was to discuss the current status of mesenchymal stem cells, with an emphasis on adipose-derived stem cells (ADSCs), in combination with plasma gel, glue fibrin, and membranes (scaffold). The use of gels and membranes supports cell growth, and aims at potential application in reconstructive plastic surgery for the treatment of burn patients or individuals requiring skin grafts. This study explores and discusses the role of mesenchymal stem cells, adipose-derived mesenchymal stem cells, glue fibrin, plasma gel, and the scaffold. This research collected information from the Virtual Health Library (VHL) and PubMed. A considerable number of articles have been published on burn treatment. However, there is little research on burn treatment with ADSCs, glue fibrin, plasma gel, and scaffold. An ADSC autograft combined with a biological dressing is promising in reconstructive plastic surgery for the treatment and recovery of burn patients or individuals with other injuries that require skin grafts. These features can reduce pain and aid in drying of the lesion, thus promoting neovascularization and wound reepithelialization. |
| first_indexed | 2024-03-09T06:03:20Z |
| format | Article |
| id | doaj.art-6a1f9691230648668a3ddf8f12d92f37 |
| institution | Directory Open Access Journal |
| issn | 1983-5175 2177-1235 |
| language | English |
| last_indexed | 2024-03-09T06:03:20Z |
| publishDate | 2016-09-01 |
| publisher | Sociedade Brasileira de Cirurgia Plástica |
| record_format | Article |
| series | Revista Brasileira de Cirurgia Plástica |
| spelling | doaj.art-6a1f9691230648668a3ddf8f12d92f372023-12-03T12:06:39ZengSociedade Brasileira de Cirurgia PlásticaRevista Brasileira de Cirurgia Plástica1983-51752177-12352016-09-01310341742310.5935/2177-1235.2016RBCP0068Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgeryCharlene Silvestrin Celi Garcia0Luiz Carlos Celi Garcia1João Antonio Pêgas Henriques2Mariana Roesch Ely3Paulo Miguel Celi Garcia4Instituto de Biotecnologia da Universidade de Caxias do Sul, Caxias do Sul, RS, BrazilInstituto de Biotecnologia da Universidade de Caxias do Sul, Caxias do Sul, RS, BrazilInstituto de Biotecnologia da Universidade de Caxias do Sul, Caxias do Sul, RS, BrazilInstituto de Biotecnologia da Universidade de Caxias do Sul, Caxias do Sul, RS, BrazilInstituto de Biotecnologia da Universidade de Caxias do Sul, Caxias do Sul, RS, BrazilIn Brazil, 1 million burn accidents occur annually, and subsequent wound infections account for 75% cases of deaths among these patients, in addition to inducing deformities in the affected areas. Therefore, the aim of this study was to discuss the current status of mesenchymal stem cells, with an emphasis on adipose-derived stem cells (ADSCs), in combination with plasma gel, glue fibrin, and membranes (scaffold). The use of gels and membranes supports cell growth, and aims at potential application in reconstructive plastic surgery for the treatment of burn patients or individuals requiring skin grafts. This study explores and discusses the role of mesenchymal stem cells, adipose-derived mesenchymal stem cells, glue fibrin, plasma gel, and the scaffold. This research collected information from the Virtual Health Library (VHL) and PubMed. A considerable number of articles have been published on burn treatment. However, there is little research on burn treatment with ADSCs, glue fibrin, plasma gel, and scaffold. An ADSC autograft combined with a biological dressing is promising in reconstructive plastic surgery for the treatment and recovery of burn patients or individuals with other injuries that require skin grafts. These features can reduce pain and aid in drying of the lesion, thus promoting neovascularization and wound reepithelialization.http://www.rbcp.org.br/export-pdf/1773/en_v31n3a20.pdfstem cellsreconstructive surgical proceduresbioprosthesesskinadipose tissue |
| spellingShingle | Charlene Silvestrin Celi Garcia Luiz Carlos Celi Garcia João Antonio Pêgas Henriques Mariana Roesch Ely Paulo Miguel Celi Garcia Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery Revista Brasileira de Cirurgia Plástica stem cells reconstructive surgical procedures bioprostheses skin adipose tissue |
| title | Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| title_full | Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| title_fullStr | Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| title_full_unstemmed | Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| title_short | Adipose tissue-derived stem cell autologous grafts: a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| title_sort | adipose tissue derived stem cell autologous grafts a new approach to application in the treatment of burn victims and reconstructive plastic surgery |
| topic | stem cells reconstructive surgical procedures bioprostheses skin adipose tissue |
| url | http://www.rbcp.org.br/export-pdf/1773/en_v31n3a20.pdf |
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