Inflammation and autonomic balance in cirrhosis: Association between sympathetic nervous system and osteopontin, interleukin‐22, interleukin‐6 and interleukin‐1Ra concentrations according to portal hypertension and disease severity

Inflammation and autonomic balance in cirrhosis: Association between sympathetic nervous system and osteopontin, interleukin‐22, interleukin‐6 and interleukin‐1Ra concentrations according to portal hypertension and disease severity

Abstract Background The autonomic nervous system is linked to hyperdynamic circulation in cirrhosis and several studies have highlighted the crucial role that systemic inflammation elicits in altering sympathovagal equilibrium with the consequent reduction in heart rate variability (HRV). To investi...

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Main Authors: Giuseppe Miceli, Grazia Pennisi, Luisa Agnello, Vincenza Calvaruso, Emanuele Amodio, Alessandra Casuccio, Chiara Pintus, Maria Grazia Basso, Rosaria Maria Pipitone, Mario Daidone, Rossella Zito, Giulia Lupo, Salvatore Petta, Giuseppe Cabibbo, Marcello Ciaccio, Stefania Grimaudo, Antonio CraxÌ, Antonino Tuttolomondo
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Clinical and Translational Discovery
Subjects:
cirrhosis
cytokines
heart rate variability
inflammation
portal hypertension
varices bleeding
Online Access:https://doi.org/10.1002/ctd2.215

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