Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients

Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients

BackgroundImmune checkpoint inhibitors (ICI) have shown durable and long-term benefits in a subset of head and neck squamous cell carcinoma (HNSCC) patients. To identify patient-responders from non-responders, biomarkers are needed which are predictive of outcome to ICI therapy. Cues in the tumor mi...

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Bibliographic Details
Main Authors: Arutha Kulasinghe, Touraj Taheri, Ken O’Byrne, Brett G. M. Hughes, Liz Kenny, Chamindie Punyadeera
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
head and neck cancer
head and neck squamous cell carcinoma
tumor microenvironment
digital spatial profiling
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.607349/full

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