Gender-Differences in aortic dissection

Objectives: Aortic dissection is a truly emergency in daily practice, and for gender factor, we want to compare the epidemiology, biomarkers, symptoms and outcome. Methods: A retrospective review six-year AD cases in a northern Taiwan medical center from January, 1, 2005 to December, 31, 2010. by ga...

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Main Authors: Yu-Jang Su, Che-Hung Liu, Yu-Hang Yeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Acute Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221618914600032
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author Yu-Jang Su
Che-Hung Liu
Yu-Hang Yeh
author_facet Yu-Jang Su
Che-Hung Liu
Yu-Hang Yeh
author_sort Yu-Jang Su
collection DOAJ
description Objectives: Aortic dissection is a truly emergency in daily practice, and for gender factor, we want to compare the epidemiology, biomarkers, symptoms and outcome. Methods: A retrospective review six-year AD cases in a northern Taiwan medical center from January, 1, 2005 to December, 31, 2010. by gathering data of 134 AD patients including gender, age, episodes of time, season, vital signs, symptoms (chest pain, chest tightness (CP/CT), abdominal pain, neurological symptoms), Stanford classifications, and outcome. Comparisons are made by gender of AD groups. 85 cases with complete data are strictly enrolled into our study. We used student t test and one way ANOVA for statistical analyses, and significance was set at a P value less than 0.05 (2-tailed). Results: There are 64 male and 21 female enrolled into our study with the mean ± standard deviation (SD) of age is (64.1±14.0) years old. In AD patients with female gender are older than male AD patients (71.5 vs. 61.6 years old, P value<0.01). In symptoms of presentation, female AD patients have more neurologic symptoms than male AD patients (38.1% vs. 12.5%, P <0.01). Female AD patients have longer hospital stay and higher mortality rate than male AD patients (16.8 vs. 13.4 d; 38.1% vs. 18.8%, P =0.39; P =0.07). Conclusion: Female AD patients are ten-year older in age than male, and have more common neurologic symptoms in presentations, and female AD patient have 2-fold mortality rate than male AD patients.
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spelling doaj.art-6a2ba8073f9e43aea2fe259d6ebab72a2022-12-21T23:42:39ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892014-01-0131101310.1016/S2221-6189(14)60003-2Gender-Differences in aortic dissectionYu-Jang Su0Che-Hung Liu1Yu-Hang Yeh2Department of Emergency Medicine, Mackay Memorial Hospital, No.92, Sec 2, Chung-Shan North Rd. Taipei 10449, TaiwanDepartment of Emergency Medicine, Mackay Memorial Hospital, No.92, Sec 2, Chung-Shan North Rd. Taipei 10449, TaiwanDepartment of Emergency Medicine, Taipei City Hospital, Zhongxing Branch, Taipei, TaiwanObjectives: Aortic dissection is a truly emergency in daily practice, and for gender factor, we want to compare the epidemiology, biomarkers, symptoms and outcome. Methods: A retrospective review six-year AD cases in a northern Taiwan medical center from January, 1, 2005 to December, 31, 2010. by gathering data of 134 AD patients including gender, age, episodes of time, season, vital signs, symptoms (chest pain, chest tightness (CP/CT), abdominal pain, neurological symptoms), Stanford classifications, and outcome. Comparisons are made by gender of AD groups. 85 cases with complete data are strictly enrolled into our study. We used student t test and one way ANOVA for statistical analyses, and significance was set at a P value less than 0.05 (2-tailed). Results: There are 64 male and 21 female enrolled into our study with the mean ± standard deviation (SD) of age is (64.1±14.0) years old. In AD patients with female gender are older than male AD patients (71.5 vs. 61.6 years old, P value<0.01). In symptoms of presentation, female AD patients have more neurologic symptoms than male AD patients (38.1% vs. 12.5%, P <0.01). Female AD patients have longer hospital stay and higher mortality rate than male AD patients (16.8 vs. 13.4 d; 38.1% vs. 18.8%, P =0.39; P =0.07). Conclusion: Female AD patients are ten-year older in age than male, and have more common neurologic symptoms in presentations, and female AD patient have 2-fold mortality rate than male AD patients.http://www.sciencedirect.com/science/article/pii/S2221618914600032Sex differenceAortic dissectionHospital mortality
spellingShingle Yu-Jang Su
Che-Hung Liu
Yu-Hang Yeh
Gender-Differences in aortic dissection
Journal of Acute Disease
Sex difference
Aortic dissection
Hospital mortality
title Gender-Differences in aortic dissection
title_full Gender-Differences in aortic dissection
title_fullStr Gender-Differences in aortic dissection
title_full_unstemmed Gender-Differences in aortic dissection
title_short Gender-Differences in aortic dissection
title_sort gender differences in aortic dissection
topic Sex difference
Aortic dissection
Hospital mortality
url http://www.sciencedirect.com/science/article/pii/S2221618914600032
work_keys_str_mv AT yujangsu genderdifferencesinaorticdissection
AT chehungliu genderdifferencesinaorticdissection
AT yuhangyeh genderdifferencesinaorticdissection