Scandium Radioisotopes—Toward New Targets and Imaging Modalities
The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/22/7668 |
| _version_ | 1827639128160731136 |
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| author | Krzysztof Kilian Krystyna Pyrzyńska |
| author_facet | Krzysztof Kilian Krystyna Pyrzyńska |
| author_sort | Krzysztof Kilian |
| collection | DOAJ |
| description | The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice. |
| first_indexed | 2024-03-09T16:34:18Z |
| format | Article |
| id | doaj.art-6a35ea6afa7548d0bcd808b962e32cfd |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T16:34:18Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6a35ea6afa7548d0bcd808b962e32cfd2023-11-24T14:58:38ZengMDPI AGMolecules1420-30492023-11-012822766810.3390/molecules28227668Scandium Radioisotopes—Toward New Targets and Imaging ModalitiesKrzysztof Kilian0Krystyna Pyrzyńska1Heavy Ion Laboratory, University of Warsaw, Pasteura 5a, 02-093 Warsaw, PolandFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, PolandThe concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice.https://www.mdpi.com/1420-3049/28/22/7668theranosticsscandium radioisotopesradiolabelingradiopharmaceuticalsradiochemical separation |
| spellingShingle | Krzysztof Kilian Krystyna Pyrzyńska Scandium Radioisotopes—Toward New Targets and Imaging Modalities Molecules theranostics scandium radioisotopes radiolabeling radiopharmaceuticals radiochemical separation |
| title | Scandium Radioisotopes—Toward New Targets and Imaging Modalities |
| title_full | Scandium Radioisotopes—Toward New Targets and Imaging Modalities |
| title_fullStr | Scandium Radioisotopes—Toward New Targets and Imaging Modalities |
| title_full_unstemmed | Scandium Radioisotopes—Toward New Targets and Imaging Modalities |
| title_short | Scandium Radioisotopes—Toward New Targets and Imaging Modalities |
| title_sort | scandium radioisotopes toward new targets and imaging modalities |
| topic | theranostics scandium radioisotopes radiolabeling radiopharmaceuticals radiochemical separation |
| url | https://www.mdpi.com/1420-3049/28/22/7668 |
| work_keys_str_mv | AT krzysztofkilian scandiumradioisotopestowardnewtargetsandimagingmodalities AT krystynapyrzynska scandiumradioisotopestowardnewtargetsandimagingmodalities |