Gate-keeper of ion transport—a highly conserved helix-3 tryptophan in a channelrhodopsin chimera, C1C2/ChRWR

Gate-keeper of ion transport—a highly conserved helix-3 tryptophan in a channelrhodopsin chimera, C1C2/ChRWR

Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to W86 of bacteriorhodopsin (BR), is highly conserve...

Full description

Bibliographic Details
Main Authors: Yujiro Nagasaka, Shoko Hososhima, Naoko Kubo, Takashi Nagata, Hideki Kandori, Keiichi Inoue, Hiromu Yawo
Format: Article
Language:English
Published: The Biophysical Society of Japan 2020-07-01
Series:Biophysics and Physicobiology
Subjects:
microbial rhodopsin
retinal-binding pocket
cation channel
h+ channel
h+ pump
Online Access:https://doi.org/10.2142/biophysico.BSJ-2020007

Similar Items

Similar Items