Clinical case: multiple endocrine neoplasia type 1 (MEN 1)
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations...
Format: | Article |
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Language: | English |
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Endocrinology Research Centre
2012-12-01
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Series: | Ожирение и метаболизм |
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Online Access: | https://www.omet-endojournals.ru/jour/article/view/5129 |
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collection | DOAJ |
description | Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels. |
first_indexed | 2024-03-08T09:14:15Z |
format | Article |
id | doaj.art-6a39601c34e147fdb5657d9bf386f60c |
institution | Directory Open Access Journal |
issn | 2071-8713 2306-5524 |
language | English |
last_indexed | 2024-04-24T08:38:55Z |
publishDate | 2012-12-01 |
publisher | Endocrinology Research Centre |
record_format | Article |
series | Ожирение и метаболизм |
spelling | doaj.art-6a39601c34e147fdb5657d9bf386f60c2024-04-16T16:16:07ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242012-12-0194444710.14341/2071-8713-51295087Clinical case: multiple endocrine neoplasia type 1 (MEN 1)Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels.https://www.omet-endojournals.ru/jour/article/view/5129wermer syndromemen 1prolactinomaprolactinhyperparathyroidisminsulinomaproinsulin |
spellingShingle | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) Ожирение и метаболизм wermer syndrome men 1 prolactinoma prolactin hyperparathyroidism insulinoma proinsulin |
title | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) |
title_full | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) |
title_fullStr | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) |
title_full_unstemmed | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) |
title_short | Clinical case: multiple endocrine neoplasia type 1 (MEN 1) |
title_sort | clinical case multiple endocrine neoplasia type 1 men 1 |
topic | wermer syndrome men 1 prolactinoma prolactin hyperparathyroidism insulinoma proinsulin |
url | https://www.omet-endojournals.ru/jour/article/view/5129 |