Involvement of cannabinoid receptors in depression of the putative nociceptive response in spinal cord preparations isolated from neonatal rats

Involvement of cannabinoid receptors in depression of the putative nociceptive response in spinal cord preparations isolated from neonatal rats

Abstract A metabolite of acetaminophen, AM404, which is an anandamide transporter inhibitor, induces analgesia mainly via activation of transient receptor potential channel 1 in the spinal cord, although the role of cannabinoid receptors remains to be studied. The ventral root reflex response induce...

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Bibliographic Details
Main Authors: Kayo Tsuzawa, Hiroshi Onimaru, Katsunori Inagaki, Masahiko Izumizaki
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Physiological Sciences
Subjects:
Acetaminophen
Cannabinoid receptor
Lumbar spinal cord
Newborn rat
Online Access:https://doi.org/10.1186/s12576-023-00881-5

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