Trop-2 is a determinant of breast cancer survival.

Trop-2 is a calcium signal transducer that drives tumor growth. Anti-Trop-2 antibodies with selective reactivity versus Trop-2 maturation stages allowed to identify two different pools of Trop-2, one localized in the cell membrane and one in the cytoplasm. Of note, membrane-localized/functional Trop...

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Bibliographic Details
Main Authors: Federico Ambrogi, Marco Fornili, Patrizia Boracchi, Marco Trerotola, Valeria Relli, Pasquale Simeone, Rossana La Sorda, Rossano Lattanzio, Patrizia Querzoli, Massimo Pedriali, Mauro Piantelli, Elia Biganzoli, Saverio Alberti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4019539?pdf=render