Diagnosis of acute myocardial infarction in the emergency setting

Acute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one...

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Main Authors: Seema Bhargava, Anjali Manocha, Mamta Kankra, L M Srivastava
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Current Medicine Research and Practice
Subjects:
Online Access:http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargava
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author Seema Bhargava
Anjali Manocha
Mamta Kankra
L M Srivastava
author_facet Seema Bhargava
Anjali Manocha
Mamta Kankra
L M Srivastava
author_sort Seema Bhargava
collection DOAJ
description Acute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one of the factors affecting morbidity is the time of initiation of treatment after onset of symptoms. Hence, it is important to differentiate between AMI and unstable angina. Since ECG alone has a low sensitivity and specificity for AMI, biochemical serum markers (AST, CPK, CKMB mass, troponins, myoglobin) are used to aid diagnosis. As newer biomarkers evolve and methodologies improve, guidelines for the diagnosis of AMI have also been revised. In 2012, the European Society of Cardiology (ESC) and American College of Cardiology (ACC) have suggested guidelines for the diagnosis of AMI. Taking into consideration these guidelines, and the pathophysiology of cardiac biomarkers, an algorithm has been suggested for the diagnosis of AMI in patients presenting to the emergency department within 10 hours of onset of chest pain. This would aid in early and accurate diagnosis of AMI.
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spelling doaj.art-6a3d42d9ac2b471296752cf507c6f9d42022-12-22T04:14:08ZengWolters Kluwer Medknow PublicationsCurrent Medicine Research and Practice2352-08172352-08252013-01-01327481Diagnosis of acute myocardial infarction in the emergency settingSeema BhargavaAnjali ManochaMamta KankraL M SrivastavaAcute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one of the factors affecting morbidity is the time of initiation of treatment after onset of symptoms. Hence, it is important to differentiate between AMI and unstable angina. Since ECG alone has a low sensitivity and specificity for AMI, biochemical serum markers (AST, CPK, CKMB mass, troponins, myoglobin) are used to aid diagnosis. As newer biomarkers evolve and methodologies improve, guidelines for the diagnosis of AMI have also been revised. In 2012, the European Society of Cardiology (ESC) and American College of Cardiology (ACC) have suggested guidelines for the diagnosis of AMI. Taking into consideration these guidelines, and the pathophysiology of cardiac biomarkers, an algorithm has been suggested for the diagnosis of AMI in patients presenting to the emergency department within 10 hours of onset of chest pain. This would aid in early and accurate diagnosis of AMI.http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargavaacute myocardial infarctionacute coronary syndromectnictntmyoglobinckmb mass
spellingShingle Seema Bhargava
Anjali Manocha
Mamta Kankra
L M Srivastava
Diagnosis of acute myocardial infarction in the emergency setting
Current Medicine Research and Practice
acute myocardial infarction
acute coronary syndrome
ctni
ctnt
myoglobin
ckmb mass
title Diagnosis of acute myocardial infarction in the emergency setting
title_full Diagnosis of acute myocardial infarction in the emergency setting
title_fullStr Diagnosis of acute myocardial infarction in the emergency setting
title_full_unstemmed Diagnosis of acute myocardial infarction in the emergency setting
title_short Diagnosis of acute myocardial infarction in the emergency setting
title_sort diagnosis of acute myocardial infarction in the emergency setting
topic acute myocardial infarction
acute coronary syndrome
ctni
ctnt
myoglobin
ckmb mass
url http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargava
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