Diagnosis of acute myocardial infarction in the emergency setting
Acute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Current Medicine Research and Practice |
Subjects: | |
Online Access: | http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargava |
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author | Seema Bhargava Anjali Manocha Mamta Kankra L M Srivastava |
author_facet | Seema Bhargava Anjali Manocha Mamta Kankra L M Srivastava |
author_sort | Seema Bhargava |
collection | DOAJ |
description | Acute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one of the factors affecting morbidity is the time of initiation of treatment after onset of symptoms. Hence, it is important to differentiate between AMI and unstable angina. Since ECG alone has a low sensitivity and specificity for AMI, biochemical serum markers (AST, CPK, CKMB mass, troponins, myoglobin) are used to aid diagnosis. As newer biomarkers evolve and methodologies improve, guidelines for the diagnosis of AMI have also been revised. In 2012, the European Society of Cardiology (ESC) and American College of Cardiology (ACC) have suggested guidelines for the diagnosis of AMI. Taking into consideration these guidelines, and the pathophysiology of cardiac biomarkers, an algorithm has been suggested for the diagnosis of AMI in patients presenting to the emergency department within 10 hours of onset of chest pain. This would aid in early and accurate diagnosis of AMI. |
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format | Article |
id | doaj.art-6a3d42d9ac2b471296752cf507c6f9d4 |
institution | Directory Open Access Journal |
issn | 2352-0817 2352-0825 |
language | English |
last_indexed | 2024-04-11T16:26:59Z |
publishDate | 2013-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Current Medicine Research and Practice |
spelling | doaj.art-6a3d42d9ac2b471296752cf507c6f9d42022-12-22T04:14:08ZengWolters Kluwer Medknow PublicationsCurrent Medicine Research and Practice2352-08172352-08252013-01-01327481Diagnosis of acute myocardial infarction in the emergency settingSeema BhargavaAnjali ManochaMamta KankraL M SrivastavaAcute coronary syndrome (ACS) in the emergency setting poses a dilemma in its differential diagnosis. It encompasses a range of thrombotic coronary events including acute myocardial infarction (AMI) and unstable angina. The line of management depends upon whether or not the patient has AMI, and one of the factors affecting morbidity is the time of initiation of treatment after onset of symptoms. Hence, it is important to differentiate between AMI and unstable angina. Since ECG alone has a low sensitivity and specificity for AMI, biochemical serum markers (AST, CPK, CKMB mass, troponins, myoglobin) are used to aid diagnosis. As newer biomarkers evolve and methodologies improve, guidelines for the diagnosis of AMI have also been revised. In 2012, the European Society of Cardiology (ESC) and American College of Cardiology (ACC) have suggested guidelines for the diagnosis of AMI. Taking into consideration these guidelines, and the pathophysiology of cardiac biomarkers, an algorithm has been suggested for the diagnosis of AMI in patients presenting to the emergency department within 10 hours of onset of chest pain. This would aid in early and accurate diagnosis of AMI.http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargavaacute myocardial infarctionacute coronary syndromectnictntmyoglobinckmb mass |
spellingShingle | Seema Bhargava Anjali Manocha Mamta Kankra L M Srivastava Diagnosis of acute myocardial infarction in the emergency setting Current Medicine Research and Practice acute myocardial infarction acute coronary syndrome ctni ctnt myoglobin ckmb mass |
title | Diagnosis of acute myocardial infarction in the emergency setting |
title_full | Diagnosis of acute myocardial infarction in the emergency setting |
title_fullStr | Diagnosis of acute myocardial infarction in the emergency setting |
title_full_unstemmed | Diagnosis of acute myocardial infarction in the emergency setting |
title_short | Diagnosis of acute myocardial infarction in the emergency setting |
title_sort | diagnosis of acute myocardial infarction in the emergency setting |
topic | acute myocardial infarction acute coronary syndrome ctni ctnt myoglobin ckmb mass |
url | http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2013;volume=3;issue=2;spage=74;epage=81;aulast=Bhargava |
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