Camel-Derived Nanobodies as Potent Inhibitors of New Delhi Metallo-β-Lactamase-1 Enzyme

Camel-Derived Nanobodies as Potent Inhibitors of New Delhi Metallo-β-Lactamase-1 Enzyme

The injudicious usage of antibiotics during infections caused by Gram-negative bacteria leads to the emergence of β-lactamases. Among them, the NDM-1 enzyme poses a serious threat to human health. Developing new antibiotics or inhibiting β-lactamases might become essential to reduce and prevent bact...

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Bibliographic Details
Main Authors: Rahma Ben Abderrazek, Emna Hamdi, Alessandra Piccirilli, Sayda Dhaouadi, Serge Muyldermans, Mariagrazia Perilli, Balkiss Bouhaouala-Zahar
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
phage display
nanobodies
NDM-1
metallo-β-lactamases
β-lactamase small molecule inhibitors
Online Access:https://www.mdpi.com/1420-3049/29/7/1431

Internet

https://www.mdpi.com/1420-3049/29/7/1431

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