Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients
Phase angle (PhA) has been evidenced to be a useful survival indicator and predictor of morbi-mortality in different pathologies, but not in psychogeriatric patients. The aim of this study was to evaluate the clinical utility of PhA as a prognostic indicator of survival in a group of institutionaliz...
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MDPI AG
2023-04-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/9/2139 |
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| author | Sara Barrera Ortega Paz Redondo del Río Laura Carreño Enciso Sandra de la Cruz Marcos María Noel Massia Beatriz de Mateo Silleras |
| author_facet | Sara Barrera Ortega Paz Redondo del Río Laura Carreño Enciso Sandra de la Cruz Marcos María Noel Massia Beatriz de Mateo Silleras |
| author_sort | Sara Barrera Ortega |
| collection | DOAJ |
| description | Phase angle (PhA) has been evidenced to be a useful survival indicator and predictor of morbi-mortality in different pathologies, but not in psychogeriatric patients. The aim of this study was to evaluate the clinical utility of PhA as a prognostic indicator of survival in a group of institutionalized psychogeriatric patients. A survival study was conducted on 157 patients (46.5% dementia, 43.9% schizophrenia). Functional impairment stage, frailty, dependence, malnutrition (MNA), comorbidity, polypharmacy, BMI, and waist circumference were registered. Body composition was analyzed using a 50-kHz whole-body BIA; PhA was recorded. The association between mortality and standardized-PhA was evaluated through univariate and multivariate Cox regression models and ROC-curve. The risk of death decreased when Z-PhA, BMI, and MNA were higher. Mortality increases with age, frailty, and dependence. The risk of death was statistically significantly lower (56.5%) in patients with schizophrenia vs. dementia (89%). The Z-PhA cut-off point was −0.81 (Sensitivity:0.75; Specificity:0.60). Mortality risk was multiplied by 1.09 in subjects with a Z-PhA < −0.81, regardless of age, presence of dementia, and BMI. PhA presented a remarkable clinical utility as an independent indicator of survival in psychogeriatric patients. Moreover, it could be useful to detect disease-related malnutrition and to identify subjects eligible for an early clinical approach. |
| first_indexed | 2024-03-11T04:10:06Z |
| format | Article |
| id | doaj.art-6a411992baba41518cc11f2cd4e653c6 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T04:10:06Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-6a411992baba41518cc11f2cd4e653c62023-11-17T23:29:39ZengMDPI AGNutrients2072-66432023-04-01159213910.3390/nu15092139Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric PatientsSara Barrera Ortega0Paz Redondo del Río1Laura Carreño Enciso2Sandra de la Cruz Marcos3María Noel Massia4Beatriz de Mateo Silleras5Psycho-Geriatric Area, Assistance Center of San Juan de Dios, 34005 Palencia, SpainDepartment of Nutrition and Food Science, Faculty of Medicine, University of Valladolid, 47005 Valladolid, SpainDepartment of Nutrition and Food Science, Faculty of Medicine, University of Valladolid, 47005 Valladolid, SpainDepartment of Nutrition and Food Science, Faculty of Medicine, University of Valladolid, 47005 Valladolid, SpainPsycho-Geriatric Area, Assistance Center of San Juan de Dios, 34005 Palencia, SpainDepartment of Nutrition and Food Science, Faculty of Medicine, University of Valladolid, 47005 Valladolid, SpainPhase angle (PhA) has been evidenced to be a useful survival indicator and predictor of morbi-mortality in different pathologies, but not in psychogeriatric patients. The aim of this study was to evaluate the clinical utility of PhA as a prognostic indicator of survival in a group of institutionalized psychogeriatric patients. A survival study was conducted on 157 patients (46.5% dementia, 43.9% schizophrenia). Functional impairment stage, frailty, dependence, malnutrition (MNA), comorbidity, polypharmacy, BMI, and waist circumference were registered. Body composition was analyzed using a 50-kHz whole-body BIA; PhA was recorded. The association between mortality and standardized-PhA was evaluated through univariate and multivariate Cox regression models and ROC-curve. The risk of death decreased when Z-PhA, BMI, and MNA were higher. Mortality increases with age, frailty, and dependence. The risk of death was statistically significantly lower (56.5%) in patients with schizophrenia vs. dementia (89%). The Z-PhA cut-off point was −0.81 (Sensitivity:0.75; Specificity:0.60). Mortality risk was multiplied by 1.09 in subjects with a Z-PhA < −0.81, regardless of age, presence of dementia, and BMI. PhA presented a remarkable clinical utility as an independent indicator of survival in psychogeriatric patients. Moreover, it could be useful to detect disease-related malnutrition and to identify subjects eligible for an early clinical approach.https://www.mdpi.com/2072-6643/15/9/2139bioelectrical impedancephase angledementiaschizophreniapsychogeriatric patientsnutritional status assessment |
| spellingShingle | Sara Barrera Ortega Paz Redondo del Río Laura Carreño Enciso Sandra de la Cruz Marcos María Noel Massia Beatriz de Mateo Silleras Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients Nutrients bioelectrical impedance phase angle dementia schizophrenia psychogeriatric patients nutritional status assessment |
| title | Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients |
| title_full | Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients |
| title_fullStr | Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients |
| title_full_unstemmed | Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients |
| title_short | Phase Angle as a Prognostic Indicator of Survival in Institutionalized Psychogeriatric Patients |
| title_sort | phase angle as a prognostic indicator of survival in institutionalized psychogeriatric patients |
| topic | bioelectrical impedance phase angle dementia schizophrenia psychogeriatric patients nutritional status assessment |
| url | https://www.mdpi.com/2072-6643/15/9/2139 |
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