A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy

In late years, combination of Cisplatin and Docetaxel, S-1 (as follows: a TPS therapy) show a high effect in induction chemotherapy in the oral carcinoma, we are said to be it, and it is used. We receive TPS therapy for carcinoma in the oral floor (T2N2bM0) this time and report our experience with t...

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Main Authors: Toru Inomata, Naruhisa Tanaka, Jumpei Tanaka, Munenori Takeda, Masako Kobayashi, Yoshiki Ishigaki, Takafumi Satomi, Toshimasa Machida, Masatoshi Ide
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Advances in Oral and Maxillofacial Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667147623000171
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author Toru Inomata
Naruhisa Tanaka
Jumpei Tanaka
Munenori Takeda
Masako Kobayashi
Yoshiki Ishigaki
Takafumi Satomi
Toshimasa Machida
Masatoshi Ide
author_facet Toru Inomata
Naruhisa Tanaka
Jumpei Tanaka
Munenori Takeda
Masako Kobayashi
Yoshiki Ishigaki
Takafumi Satomi
Toshimasa Machida
Masatoshi Ide
author_sort Toru Inomata
collection DOAJ
description In late years, combination of Cisplatin and Docetaxel, S-1 (as follows: a TPS therapy) show a high effect in induction chemotherapy in the oral carcinoma, we are said to be it, and it is used. We receive TPS therapy for carcinoma in the oral floor (T2N2bM0) this time and report our experience with the case that had a complete response. 61-years-old men, with squamous cell carcinoma in the Left oral floor (T2N2bM0) was diagnosed than a clinical examination and image findings, an examination of histopathology. Because it was local progressive carcinoma, perform induction chemotherapy in a TPS therapy preoperative tumor reduction. The primary tumor, the cervical metastasis lymph nodes reduced after 1 course end remarkably. We performed floor of mouth part tumor resection and all left neck dissection. The histologic effect of treatment judgment were Grade3 for histopathology. Resist evaluation was CR. We follow it up, but it is primary and the cervical lymph nodes recurrence does not show it now either.
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spelling doaj.art-6a4ec50f83664d9792fd45b655b2c6592023-05-02T04:05:23ZengElsevierAdvances in Oral and Maxillofacial Surgery2667-14762023-06-0110100405A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapyToru Inomata0Naruhisa Tanaka1Jumpei Tanaka2Munenori Takeda3Masako Kobayashi4Yoshiki Ishigaki5Takafumi Satomi6Toshimasa Machida7Masatoshi Ide8Department of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, Japan; Corresponding author. Department of Oral and Maxillofacial Surgery, Nippon Dental University, 2-3-16 Fujimi, Chiyoda-ku, Tokyo, 102-8158, Japan.Department of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Nippon Dental University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Sainokuni Higashiomiya Medical, Center, JapanDepartment of Oral and Maxillofacial Surgery, Fuji City General Hospital, JapanIn late years, combination of Cisplatin and Docetaxel, S-1 (as follows: a TPS therapy) show a high effect in induction chemotherapy in the oral carcinoma, we are said to be it, and it is used. We receive TPS therapy for carcinoma in the oral floor (T2N2bM0) this time and report our experience with the case that had a complete response. 61-years-old men, with squamous cell carcinoma in the Left oral floor (T2N2bM0) was diagnosed than a clinical examination and image findings, an examination of histopathology. Because it was local progressive carcinoma, perform induction chemotherapy in a TPS therapy preoperative tumor reduction. The primary tumor, the cervical metastasis lymph nodes reduced after 1 course end remarkably. We performed floor of mouth part tumor resection and all left neck dissection. The histologic effect of treatment judgment were Grade3 for histopathology. Resist evaluation was CR. We follow it up, but it is primary and the cervical lymph nodes recurrence does not show it now either.http://www.sciencedirect.com/science/article/pii/S2667147623000171TPS therapyInduction chemotherapyOral carcinomaLocal progressive carcinomaHistopathology
spellingShingle Toru Inomata
Naruhisa Tanaka
Jumpei Tanaka
Munenori Takeda
Masako Kobayashi
Yoshiki Ishigaki
Takafumi Satomi
Toshimasa Machida
Masatoshi Ide
A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
Advances in Oral and Maxillofacial Surgery
TPS therapy
Induction chemotherapy
Oral carcinoma
Local progressive carcinoma
Histopathology
title A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
title_full A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
title_fullStr A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
title_full_unstemmed A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
title_short A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy
title_sort case of carcinoma of the oral floor treated successfully with the tps therapy as an induction chemotherapy
topic TPS therapy
Induction chemotherapy
Oral carcinoma
Local progressive carcinoma
Histopathology
url http://www.sciencedirect.com/science/article/pii/S2667147623000171
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