Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women
Abstract Background The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density...
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| Format: | Article |
| Language: | English |
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BMC
2021-10-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-021-04748-x |
| _version_ | 1818719135236882432 |
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| author | Geise Ferreira da Cruz Tatiana Mion Lunz Tatielle Rocha de Jesus Mariana Braga Costa Camila Vilarinho Vidigal Ben-Hur Albergaria Jose Luiz Marques-Rocha Valdete Regina Guandalini |
| author_facet | Geise Ferreira da Cruz Tatiana Mion Lunz Tatielle Rocha de Jesus Mariana Braga Costa Camila Vilarinho Vidigal Ben-Hur Albergaria Jose Luiz Marques-Rocha Valdete Regina Guandalini |
| author_sort | Geise Ferreira da Cruz |
| collection | DOAJ |
| description | Abstract Background The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density (BMD) categories of postmenopausal women. Methods In this cross-sectional study with a probabilistic sample, sociodemographic, lifestyle, menopause time, anthropometric, and physical activity variables were collected. ASMI and BMD were assessed by dual-energy X-ray absorptiometry (DXA). Participants were grouped according to BMD values into normal density, osteopenia, and osteoporosis. Multivariate logistic regression models were applied to verify the influence of ASMI on BMD. Data were analyzed using the SPSS statistical software, version 22. The significance level for all tests was set at 5%. Results Of the 114 women analyzed, most were between 60 and 69.9 years of age (62.3%), on menopause for ≤19.0 (51.8%), self-declared brown race/color (49.1%), had < 4 years of education (41.2%), never smoked (69.0%) or drank alcohol (62.8%). Of these, 52.6% were classified as sufficiently active and 52.2% had regular sun exposure. Women with osteoporosis were older (p = 0.035), on menopause for a longer time (p = 0.011), underweight (p = 0.004), had adequate waist circumference (p = 0.017), and low ASMI values (p = 0.002). There was an association between the 1st tertile of ASMI and osteoporosis. However, after adjustments for age, race/color, and body mass index, the strength of association between BMD and ASMI was not maintained. Conclusions ASMI was not associated with the BMD of the postmenopausal women evaluated. Total body and muscle mass, in addition to bone mass, should be monitored during menopause treatment. Longitudinal studies must be conducted to elucidate the mechanisms and gaps in this relationship. |
| first_indexed | 2024-12-17T20:02:08Z |
| format | Article |
| id | doaj.art-6a55507c05db45b794eb3d9b5308008a |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-17T20:02:08Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-6a55507c05db45b794eb3d9b5308008a2022-12-21T21:34:26ZengBMCBMC Musculoskeletal Disorders1471-24742021-10-012211910.1186/s12891-021-04748-xInfluence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal womenGeise Ferreira da Cruz0Tatiana Mion Lunz1Tatielle Rocha de Jesus2Mariana Braga Costa3Camila Vilarinho Vidigal4Ben-Hur Albergaria5Jose Luiz Marques-Rocha6Valdete Regina Guandalini7Postgraduate Program in Nutrition and Health, Federal University of Espirito SantoDepartment of Integrated Education, Federal University of Espirito SantoDepartment of Integrated Education, Federal University of Espirito SantoDepartment of Integrated Education, Federal University of Espirito SantoDepartment of Integrated Education, Federal University of Espirito SantoDepartment of Social Medicine, Federal University of Espirito SantoPostgraduate Program in Nutrition and Health, Federal University of Espirito SantoPostgraduate Program in Nutrition and Health, Federal University of Espirito SantoAbstract Background The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density (BMD) categories of postmenopausal women. Methods In this cross-sectional study with a probabilistic sample, sociodemographic, lifestyle, menopause time, anthropometric, and physical activity variables were collected. ASMI and BMD were assessed by dual-energy X-ray absorptiometry (DXA). Participants were grouped according to BMD values into normal density, osteopenia, and osteoporosis. Multivariate logistic regression models were applied to verify the influence of ASMI on BMD. Data were analyzed using the SPSS statistical software, version 22. The significance level for all tests was set at 5%. Results Of the 114 women analyzed, most were between 60 and 69.9 years of age (62.3%), on menopause for ≤19.0 (51.8%), self-declared brown race/color (49.1%), had < 4 years of education (41.2%), never smoked (69.0%) or drank alcohol (62.8%). Of these, 52.6% were classified as sufficiently active and 52.2% had regular sun exposure. Women with osteoporosis were older (p = 0.035), on menopause for a longer time (p = 0.011), underweight (p = 0.004), had adequate waist circumference (p = 0.017), and low ASMI values (p = 0.002). There was an association between the 1st tertile of ASMI and osteoporosis. However, after adjustments for age, race/color, and body mass index, the strength of association between BMD and ASMI was not maintained. Conclusions ASMI was not associated with the BMD of the postmenopausal women evaluated. Total body and muscle mass, in addition to bone mass, should be monitored during menopause treatment. Longitudinal studies must be conducted to elucidate the mechanisms and gaps in this relationship.https://doi.org/10.1186/s12891-021-04748-xOsteoporosis. Menopause. Body composition. DensitometrySarcopenia |
| spellingShingle | Geise Ferreira da Cruz Tatiana Mion Lunz Tatielle Rocha de Jesus Mariana Braga Costa Camila Vilarinho Vidigal Ben-Hur Albergaria Jose Luiz Marques-Rocha Valdete Regina Guandalini Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women BMC Musculoskeletal Disorders Osteoporosis. Menopause. Body composition. Densitometry Sarcopenia |
| title | Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| title_full | Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| title_fullStr | Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| title_full_unstemmed | Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| title_short | Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| title_sort | influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women |
| topic | Osteoporosis. Menopause. Body composition. Densitometry Sarcopenia |
| url | https://doi.org/10.1186/s12891-021-04748-x |
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