Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria

Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria

Novel antitubercular compounds are urgently needed to combat drug-resistant <i>Mycobacterium tuberculosis</i> (Mtb). Filamentous actinobacteria have historically been an excellent source of antitubercular drugs. Despite this, drug discovery from these microorganisms has fallen out of fav...

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Bibliographic Details
Main Authors: Daniel J. Watson, Lubbe Wiesner, Tlhalefo Matimela, Denzil Beukes, Paul R. Meyers
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
antitubercular
filamentous actinobacteria
HPLC-MS/MS
natural products
zone of inhibition
Online Access:https://www.mdpi.com/1420-3049/28/11/4276

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