Precision Medicine: Changing the way we think about healthcare

Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis an...

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Main Authors: Gustavo Rosa Gameiro, Viktor Sinkunas, Gabriel Romero Liguori, José Otavio Costa Auler-Júnior
Format: Article
Language:English
Published: Elsevier España 2018-12-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100310&lng=en&tlng=en
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author Gustavo Rosa Gameiro
Viktor Sinkunas
Gabriel Romero Liguori
José Otavio Costa Auler-Júnior
author_facet Gustavo Rosa Gameiro
Viktor Sinkunas
Gabriel Romero Liguori
José Otavio Costa Auler-Júnior
author_sort Gustavo Rosa Gameiro
collection DOAJ
description Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it occurs and, if it cannot be avoided, treats the disease in a personalized manner. Precision Medicine is that new way of thinking about medicine. In this paper, we performed a thorough review of the literature to present an updated review on the subject, discussing the impact of the use of genetics and genomics in the care process as well as medical education, clinical research and ethical issues. The Precision Medicine model is expanded upon in this article to include its principles of prediction, prevention, personalization and participation. Finally, we discuss Precision Medicine in various specialty fields and how it has been implemented in developing countries and its effects on public health and medical education.
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spelling doaj.art-6a5a2025cd2d42759daee567cf765f542022-12-22T01:21:18ZengElsevier EspañaClinics1980-53222018-12-0173010.6061/clinics/2017/e723S1807-59322018000100310Precision Medicine: Changing the way we think about healthcareGustavo Rosa GameiroViktor SinkunasGabriel Romero LiguoriJosé Otavio Costa Auler-JúniorHealth care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it occurs and, if it cannot be avoided, treats the disease in a personalized manner. Precision Medicine is that new way of thinking about medicine. In this paper, we performed a thorough review of the literature to present an updated review on the subject, discussing the impact of the use of genetics and genomics in the care process as well as medical education, clinical research and ethical issues. The Precision Medicine model is expanded upon in this article to include its principles of prediction, prevention, personalization and participation. Finally, we discuss Precision Medicine in various specialty fields and how it has been implemented in developing countries and its effects on public health and medical education.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100310&lng=en&tlng=enPrecision MedicineMedical EducationMolecular BiologyGeneticsGenomics
spellingShingle Gustavo Rosa Gameiro
Viktor Sinkunas
Gabriel Romero Liguori
José Otavio Costa Auler-Júnior
Precision Medicine: Changing the way we think about healthcare
Clinics
Precision Medicine
Medical Education
Molecular Biology
Genetics
Genomics
title Precision Medicine: Changing the way we think about healthcare
title_full Precision Medicine: Changing the way we think about healthcare
title_fullStr Precision Medicine: Changing the way we think about healthcare
title_full_unstemmed Precision Medicine: Changing the way we think about healthcare
title_short Precision Medicine: Changing the way we think about healthcare
title_sort precision medicine changing the way we think about healthcare
topic Precision Medicine
Medical Education
Molecular Biology
Genetics
Genomics
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100310&lng=en&tlng=en
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AT joseotaviocostaaulerjunior precisionmedicinechangingthewaywethinkabouthealthcare