Differential Proteomic Analysis of Astrocytes and Astrocytes-Derived Extracellular Vesicles from Control and Rai Knockout Mice: Insights into the Mechanisms of Neuroprotection

Differential Proteomic Analysis of Astrocytes and Astrocytes-Derived Extracellular Vesicles from Control and Rai Knockout Mice: Insights into the Mechanisms of Neuroprotection

Reactive astrocytes are a hallmark of neurodegenerative disease including multiple sclerosis. It is widely accepted that astrocytes may adopt alternative phenotypes depending on a combination of environmental cues and intrinsic features in a highly plastic and heterogeneous manner. However, we still...

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Bibliographic Details
Main Authors: Tommaso Montecchi, Enxhi Shaba, Domiziana De Tommaso, Fabrizio Di Giuseppe, Stefania Angelucci, Luca Bini, Claudia Landi, Cosima Tatiana Baldari, Cristina Ulivieri
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
molecular adaptor
IL-17
proteomics
extracellular vesicles
HIF-1α
Online Access:https://www.mdpi.com/1422-0067/22/15/7933

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