pitolisant, a novel histamine-3 receptor competitive antagonist, and inverse agonist, in the treatment of excessive daytime sleepiness in adult patients with narcolepsy

Narcolepsy is a debilitating sleep disorder that presents with excessive daytime sleepiness (EDS) and cataplexy, which is a sudden paralysis of muscle tone triggered by strong emotions such as laughing. It is also associated with many other disorders, including psychiatric disorders, neurologic illn...

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Bibliographic Details
Main Authors: Noeen Sarfraz, David Okuampa, Hannah Hansen, Mark Alvarez, Elyse M. Cornett, Juyeon Kakazu, Adam M. Kaye, Alan D. Kaye
Format: Article
Language:English
Published: Open Medical Publishing 2022-05-01
Series:Health Psychology Research
Online Access:https://healthpsychologyresearch.openmedicalpublishing.org/article/34222-pitolisant-a-novel-histamine-3-receptor-competitive-antagonist-and-inverse-agonist-in-the-treatment-of-excessive-daytime-sleepiness-in-adult-patien