Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.

Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.

BACKGROUND: Tumor necrosis factor receptor-associated factors (TRAFs) are important signaling molecules for a variety of pro-atherogenic cytokines including CD40L, TNF alpha, and IL1beta. Several lines of evidence identified TRAF6 as a pro-inflammatory signaling molecule in vitro and we previously d...

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Bibliographic Details
Main Authors: Peter Stachon, Anna Missiou, Carina Walter, Nerea Varo, Christian Colberg, Dennis Wolf, Maike Buchner, Constantin von Zur Mühlen, Katja Zirlik, Christoph Bode, Andreas Zirlik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2904388?pdf=render

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