miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1

miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1

Abstract Background Thioredoxin reductase 1 (TXNRD1) is an antioxidant enzyme reportedly overexpressed in hepatocellular carcinoma (HCC); however, the detailed function and mechanisms of TXNRD1 in HCC remain obscure. In this study, we investigated the miR-125b-5p-specific regulation of TXNRD1 levels...

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Bibliographic Details
Main Authors: Shengni Hua, Yingyao Quan, Meixiao Zhan, Huaxin Liao, Yong Li, Ligong Lu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cancer Cell International
Subjects:
miR-125b-5p
Hepatocellular carcinoma
Proliferation
TXNRD1
Online Access:http://link.springer.com/article/10.1186/s12935-019-0919-6

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