Imaging features of rhinocerebral mucormycosis: A study of 43 patients
Background: Rhinocerebral mucormycosis is a life-threatening infection caused by saprophytic fungi seen almost exclusively in immunocompromised patients.The objective of this study was to describe the imaging findings in patients with rhinocerebral mucormycosis. Materials and methods: The case recor...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-06-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X18300019 |
| _version_ | 1818176582938787840 |
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| author | Jacob Therakathu Shailesh Prabhu Aparna Irodi Sniya Valsa Sudhakar Vikas K. Yadav V. Rupa |
| author_facet | Jacob Therakathu Shailesh Prabhu Aparna Irodi Sniya Valsa Sudhakar Vikas K. Yadav V. Rupa |
| author_sort | Jacob Therakathu |
| collection | DOAJ |
| description | Background: Rhinocerebral mucormycosis is a life-threatening infection caused by saprophytic fungi seen almost exclusively in immunocompromised patients.The objective of this study was to describe the imaging findings in patients with rhinocerebral mucormycosis.
Materials and methods: The case records of patients with biopsy/culture proven invasive rhinocerebral mucormycosis were reviewed. Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI) images were retrieved from the Picture Archiving and Communication System (PACS) and analyzed. Statistical analysis was performed using descriptive statistics.
Results: CT and MR imaging of 43 patients showed predominant involvement of the ethmoid (37, 86%) and maxillary (34, 79%) sinuses. Extension to the orbit (32, 76%) and face (24, 57%) preceded involvement of the deep skull base (5, 12%) and brain (13, 31%). CT showed minimally enhancing hypodense soft tissue thickening as the predominant finding in involved areas, while MRI showed T2 isointense to mildly hypointense soft tissue thickening and heterogeneous post contrast enhancement as the main finding. Bone erosion was seen less often (17, 40%), with rest (26, 60%) of the patients showing extrasinus extension across grossly intact appearing bones on imaging.
Conclusion: CT and MRI shows a spectrum of findings in rhinocerebral mucormycosis. Imaging plays a major role in assessing the extent of involvement and complications. |
| first_indexed | 2024-12-11T20:18:29Z |
| format | Article |
| id | doaj.art-6a6f52c955834817ae041bc9adaaff94 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-11T20:18:29Z |
| publishDate | 2018-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-6a6f52c955834817ae041bc9adaaff942022-12-22T00:52:07ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2018-06-0149244745210.1016/j.ejrnm.2018.01.001Imaging features of rhinocerebral mucormycosis: A study of 43 patientsJacob TherakathuShailesh PrabhuAparna IrodiSniya Valsa SudhakarVikas K. YadavV. RupaBackground: Rhinocerebral mucormycosis is a life-threatening infection caused by saprophytic fungi seen almost exclusively in immunocompromised patients.The objective of this study was to describe the imaging findings in patients with rhinocerebral mucormycosis. Materials and methods: The case records of patients with biopsy/culture proven invasive rhinocerebral mucormycosis were reviewed. Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI) images were retrieved from the Picture Archiving and Communication System (PACS) and analyzed. Statistical analysis was performed using descriptive statistics. Results: CT and MR imaging of 43 patients showed predominant involvement of the ethmoid (37, 86%) and maxillary (34, 79%) sinuses. Extension to the orbit (32, 76%) and face (24, 57%) preceded involvement of the deep skull base (5, 12%) and brain (13, 31%). CT showed minimally enhancing hypodense soft tissue thickening as the predominant finding in involved areas, while MRI showed T2 isointense to mildly hypointense soft tissue thickening and heterogeneous post contrast enhancement as the main finding. Bone erosion was seen less often (17, 40%), with rest (26, 60%) of the patients showing extrasinus extension across grossly intact appearing bones on imaging. Conclusion: CT and MRI shows a spectrum of findings in rhinocerebral mucormycosis. Imaging plays a major role in assessing the extent of involvement and complications.http://www.sciencedirect.com/science/article/pii/S0378603X18300019Eye infectionsFungalMucormycosisSinusitis |
| spellingShingle | Jacob Therakathu Shailesh Prabhu Aparna Irodi Sniya Valsa Sudhakar Vikas K. Yadav V. Rupa Imaging features of rhinocerebral mucormycosis: A study of 43 patients The Egyptian Journal of Radiology and Nuclear Medicine Eye infections Fungal Mucormycosis Sinusitis |
| title | Imaging features of rhinocerebral mucormycosis: A study of 43 patients |
| title_full | Imaging features of rhinocerebral mucormycosis: A study of 43 patients |
| title_fullStr | Imaging features of rhinocerebral mucormycosis: A study of 43 patients |
| title_full_unstemmed | Imaging features of rhinocerebral mucormycosis: A study of 43 patients |
| title_short | Imaging features of rhinocerebral mucormycosis: A study of 43 patients |
| title_sort | imaging features of rhinocerebral mucormycosis a study of 43 patients |
| topic | Eye infections Fungal Mucormycosis Sinusitis |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X18300019 |
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