Coronavirus Infection in a Child of the First Year of Life: a Case Report

INTRODUCTION. Over the past few months, the topic of multisystem inflammatory syndrome in children has been evolving at anextraordinary pace, as evidenced by the increasing number of publications on this subject. The disease does not begin to developimmediately, not at the moment the virus enters th...

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Main Authors: Nailya R. Hafizova, Dinara R. Merzlyakova, Natalia A. Druzhinina, Galina P. Shiryaeva, Tatiana B. Khayretdinova, Liliya R. Imaeva, Gulnaz A. Vakhitova, Aliya R. Khabibullina, Alfiya I. Nazarova
Format: Article
Language:English
Published: Ministry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and Balneology 2023-08-01
Series:Вестник восстановительной медицины
Subjects:
Online Access:http://www.vvmr.ru/en/archives/2022/4-21-avgust-2022/klinicheskiy-sluchay/2022-21-koronavirusnaya-infekciya-u-rebnka-pervogo-goda-zhizni-klinicheskii-sluchai.html
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author Nailya R. Hafizova
Dinara R. Merzlyakova
Natalia A. Druzhinina
Galina P. Shiryaeva
Tatiana B. Khayretdinova
Liliya R. Imaeva
Gulnaz A. Vakhitova
Aliya R. Khabibullina
Alfiya I. Nazarova
author_facet Nailya R. Hafizova
Dinara R. Merzlyakova
Natalia A. Druzhinina
Galina P. Shiryaeva
Tatiana B. Khayretdinova
Liliya R. Imaeva
Gulnaz A. Vakhitova
Aliya R. Khabibullina
Alfiya I. Nazarova
author_sort Nailya R. Hafizova
collection DOAJ
description INTRODUCTION. Over the past few months, the topic of multisystem inflammatory syndrome in children has been evolving at anextraordinary pace, as evidenced by the increasing number of publications on this subject. The disease does not begin to developimmediately, not at the moment the virus enters the body, but after some time, and that is 14-21 days later. This is evidenced by thepresence of IgG antibodies and the absence of RNA virus in the biological loci. Representatives of the Pediatric Intensive Care Society ofGreat Britain felt it necessary to circulate the “PICS Statement”, which contained data on the increasing number of children with a newmultisystem inflammatory disease associated with positive tests for SARS-CoV-2. However, it should be noted that this associationwas confirmed in only some patients by appropriate tests performed in laboratory settings. The course of the disease was similar toa toxic shock syndrome and atypical Kawasaki disease, for which the characteristic symptoms are heart disease, abdominal pain andgastrointestinal symptoms. The patients showed abnormalities in blood parameters, changes in the number of blood corpuscules, thelevel of C-reactive protein (CRP), ferritin, troponin, brain natriuretic propeptide (NT-proBNP) was high.AIM. Using a case study to show the importance of a timely detection, treatment and follow-up of children with a new coronavirusinfection.MATERIAL AND METHODS. The mother of a 3-month-old child (the subject of the study) applied to the follow-up office of theRepublican Children’s Clinical Hospital in Ufa with a history of COVID-19 infection. The following were used to diagnose the currentcondition: copying of data from medical records, clinical examination with assessment of physical and psychomotor development,consultations of single-skilled specialists to make a diagnosis, laboratory and instrumental examinations.RESULTS AND DISCUSSION. The article presents an observation of a 1-year-old patient with COVID-19 infection complicatedby multisystem inflammatory syndrome, including the Kawasaki syndrome. In this patient, against the background of the thirdhospitalization for COVID-19, a positive dynamics of the course of the disease was achieved with discharge to the outpatient stage oftreatment and follow-up.CONCLUSION. Lesions of organs and organ systems caused by COVID-19 require an integrated approach to diagnosis and managementof patients. Further accumulation of data on diagnosis and clinical course of the new coronavirus infection in children remains an urgentscientific and practical task.
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spelling doaj.art-6a7511dcdefb43a1b5ddb5ad013a43e12023-07-17T14:47:14ZengMinistry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and BalneologyВестник восстановительной медицины2078-19622713-26252023-08-01214106114https://doi.org/10.38025/2078-1962-2022-21-4-106-114Coronavirus Infection in a Child of the First Year of Life: a Case ReportNailya R. Hafizova0https://orcid.org/0000-0002-1452-9998Dinara R. Merzlyakova1https://orcid.org/0000-0001-9037-7124Natalia A. Druzhinina2https://orcid.org/0000-0002-1890-2470Galina P. Shiryaeva3https://orcid.org/0000-0002-8137-4463Tatiana B. Khayretdinova4https://orcid.org/0000-0002-0460-2602Liliya R. Imaeva5https://orcid.org/0000-0002-6735-4896Gulnaz A. Vakhitova6https://orcid.org/0000-0001-9452-0901Aliya R. Khabibullina7https://orcid.org/0000-0003-2356-6667Alfiya I. Nazarova8https://orcid.org/0000-0002-6943-3096Bashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian Federation; Republican Children’s Clinical Hospital, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationBashkir State Medical University, Ufa, Russian FederationINTRODUCTION. Over the past few months, the topic of multisystem inflammatory syndrome in children has been evolving at anextraordinary pace, as evidenced by the increasing number of publications on this subject. The disease does not begin to developimmediately, not at the moment the virus enters the body, but after some time, and that is 14-21 days later. This is evidenced by thepresence of IgG antibodies and the absence of RNA virus in the biological loci. Representatives of the Pediatric Intensive Care Society ofGreat Britain felt it necessary to circulate the “PICS Statement”, which contained data on the increasing number of children with a newmultisystem inflammatory disease associated with positive tests for SARS-CoV-2. However, it should be noted that this associationwas confirmed in only some patients by appropriate tests performed in laboratory settings. The course of the disease was similar toa toxic shock syndrome and atypical Kawasaki disease, for which the characteristic symptoms are heart disease, abdominal pain andgastrointestinal symptoms. The patients showed abnormalities in blood parameters, changes in the number of blood corpuscules, thelevel of C-reactive protein (CRP), ferritin, troponin, brain natriuretic propeptide (NT-proBNP) was high.AIM. Using a case study to show the importance of a timely detection, treatment and follow-up of children with a new coronavirusinfection.MATERIAL AND METHODS. The mother of a 3-month-old child (the subject of the study) applied to the follow-up office of theRepublican Children’s Clinical Hospital in Ufa with a history of COVID-19 infection. The following were used to diagnose the currentcondition: copying of data from medical records, clinical examination with assessment of physical and psychomotor development,consultations of single-skilled specialists to make a diagnosis, laboratory and instrumental examinations.RESULTS AND DISCUSSION. The article presents an observation of a 1-year-old patient with COVID-19 infection complicatedby multisystem inflammatory syndrome, including the Kawasaki syndrome. In this patient, against the background of the thirdhospitalization for COVID-19, a positive dynamics of the course of the disease was achieved with discharge to the outpatient stage oftreatment and follow-up.CONCLUSION. Lesions of organs and organ systems caused by COVID-19 require an integrated approach to diagnosis and managementof patients. Further accumulation of data on diagnosis and clinical course of the new coronavirus infection in children remains an urgentscientific and practical task.http://www.vvmr.ru/en/archives/2022/4-21-avgust-2022/klinicheskiy-sluchay/2022-21-koronavirusnaya-infekciya-u-rebnka-pervogo-goda-zhizni-klinicheskii-sluchai.htmlsars-cov-2childrenmultisystem inflammatory responsekawasaki syndromecoursetreatment
spellingShingle Nailya R. Hafizova
Dinara R. Merzlyakova
Natalia A. Druzhinina
Galina P. Shiryaeva
Tatiana B. Khayretdinova
Liliya R. Imaeva
Gulnaz A. Vakhitova
Aliya R. Khabibullina
Alfiya I. Nazarova
Coronavirus Infection in a Child of the First Year of Life: a Case Report
Вестник восстановительной медицины
sars-cov-2
children
multisystem inflammatory response
kawasaki syndrome
course
treatment
title Coronavirus Infection in a Child of the First Year of Life: a Case Report
title_full Coronavirus Infection in a Child of the First Year of Life: a Case Report
title_fullStr Coronavirus Infection in a Child of the First Year of Life: a Case Report
title_full_unstemmed Coronavirus Infection in a Child of the First Year of Life: a Case Report
title_short Coronavirus Infection in a Child of the First Year of Life: a Case Report
title_sort coronavirus infection in a child of the first year of life a case report
topic sars-cov-2
children
multisystem inflammatory response
kawasaki syndrome
course
treatment
url http://www.vvmr.ru/en/archives/2022/4-21-avgust-2022/klinicheskiy-sluchay/2022-21-koronavirusnaya-infekciya-u-rebnka-pervogo-goda-zhizni-klinicheskii-sluchai.html
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AT aliyarkhabibullina coronavirusinfectioninachildofthefirstyearoflifeacasereport
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