Angiotensin II induces NF-κB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC- andRho kinase-dependent manner

Angiotensin II induces NF-κB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC- andRho kinase-dependent manner

Angiotensin II (ANG II), the main effector of the renin-angiotensin system, is implicated in endothelial permeability, recruitment and activation of the immune cells, and also vascular remodeling through induction of inflammatory genes. Matrix metalloproteinases (MMPs) are considered to be important...

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Bibliographic Details
Main Authors: H. Yaghooti, M. Firoozrai, S. Fallah, M.R. Khorramizadeh
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Angiotensin II
Signaling
MMP-9
Monocytic cell
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300003&lng=en&tlng=en

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