Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer

Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer

MACC1 is a prognostic and predictive metastasis biomarker for more than 20 solid cancer entities. However, its role in cancer metabolism is not sufficiently explored. Here, we report on how MACC1 impacts the use of glucose, glutamine, lactate, pyruvate and fatty acids and show the comprehensive anal...

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Bibliographic Details
Main Authors: Jan Lisec, Dennis Kobelt, Wolfgang Walther, Margarita Mokrizkij, Carsten Grötzinger, Carsten Jaeger, Katharina Baum, Mareike Simon, Jana Wolf, Nicola Beindorff, Winfried Brenner, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
MACC1
cancer metabolism
metabolic profiling
metabolic networks
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/13/5/978

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