Effects of Aging and Disease Conditions in Brain of Tumor-Bearing Mice: Evaluation of Purine DNA Damages and Fatty Acid Pool Changes

Effects of Aging and Disease Conditions in Brain of Tumor-Bearing Mice: Evaluation of Purine DNA Damages and Fatty Acid Pool Changes

The consequences of aging and disease conditions in tissues involve reactive oxygen species (ROS) and related molecular alterations of different cellular compartments. We compared a murine model of immunodeficient (SCID) xenografted young (4 weeks old) and old (17 weeks old) mice with corresponding...

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Bibliographic Details
Main Authors:	Marios G. Krokidis, Paraskevi Prasinou, Eleni K. Efthimiadou, Andrea Boari, Carla Ferreri, Chryssostomos Chatgilialoglu
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Biomolecules
Subjects:	tumor-bearing mice aging hydroxyl radical oxidatively-induced DNA lesions brain fatty acids age-induced remodeling
Online Access:	https://www.mdpi.com/2218-273X/12/8/1075

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