5-[(5-Chloro-1<i>H</i>-pyrrolo[2,3-b]pyridin-3-yl)methyl]-<i>N</i>-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine Dihydrochloride Dihydrate

5-[(5-Chloro-1<i>H</i>-pyrrolo[2,3-b]pyridin-3-yl)methyl]-<i>N</i>-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine Dihydrochloride Dihydrate

The dihydrochloride salt of pexidartinib was synthesized and the crystal structure of its dihydrate was determined from single crystal data. The asymmetric unit consists of one formula unit. In the pexidartinib molecule, the N atom of the central pyridine ring and the pyridine-N atom of the pyrrolop...

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Bibliographic Details
Main Authors: Weronika Kozanecka-Okupnik, Klaus Wurst, Sandro Neuner, Sven Nerdinger, Thomas Gelbrich
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molbank
Subjects:
crystal structure
hydrate
hydrogen bonding
kinase inhibitor
pharmaceuticals
Online Access:https://www.mdpi.com/1422-8599/2023/2/M1673

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