Current Status and Perspectives on the Application of CRISPR/Cas9 Gene-Editing System to Develop a Low-Gluten, Non-Transgenic Wheat Variety

Current Status and Perspectives on the Application of CRISPR/Cas9 Gene-Editing System to Develop a Low-Gluten, Non-Transgenic Wheat Variety

Wheat gluten contains epitopes that trigger celiac disease (CD). A life-long strict gluten-free diet is the only treatment accepted for CD. However, very low-gluten wheat may provide an alternative treatment to CD. Conventional plant breeding methods have not been sufficient to produce celiac-safe w...

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Bibliographic Details
Main Authors: Anil K. Verma, Sayanti Mandal, Aadhya Tiwari, Chiara Monachesi, Giulia N. Catassi, Akash Srivastava, Simona Gatti, Elena Lionetti, Carlo Catassi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Foods
Subjects:
celiac disease
CRISPR/Cas9
RNAi
α-gliadin
low-gluten
non-transgenic wheat
Online Access:https://www.mdpi.com/2304-8158/10/10/2351

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