Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory.
One of the greatest challenges in the treatment of substance dependence is to reverse the control that drug-associated stimuli have gained over the addict's behavior, as these drug-associated memories increase the risk of relapse even after long periods of abstinence. We report here that inhibi...
Main Authors: | Jose A Crespo, Petra Stöckl, Florian Ueberall, Marcel Jenny, Alois Saria, Gerald Zernig |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348011/pdf/?tool=EBI |
Similar Items
-
Increased conditioned place preference for cocaine in high anxiety-related behavior (HAB) mice is associated with an increased activation in the accumbens corridor
by: Janine Maria Prast, et al.
Published: (2014-12-01) -
Erasing sensorimotor memories via PKMzeta inhibition.
by: Lee Michael von Kraus, et al.
Published: (2010-06-01) -
Effects of bilateral reversible inactivation of Accumbens Nucleus on acquisition and consolidation of memory in rats
by: Abbas Ali Vafaee, et al.
Published: (2003-09-01) -
Criteria for identifying the molecular basis of the engram (CaMKII, PKMzeta)
by: John Lisman
Published: (2017-11-01) -
Nucleus accumbens core and shell are necessary for reinforcer devaluation effects on Pavlovian conditioned responding
by: Teghpal eSingh, et al.
Published: (2010-10-01)