Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis

Objective: Use of drugs that may lead to abuse or dependence are subject to controlled prescriptions (CPs) in many countries, and these are closely monitored by health authorities. According to national regulations in Turkey, CPs may be red coloured (RCPs) or green coloured (GCPs). The aim of this s...

Full description

Bibliographic Details
Main Authors: Dilek Demircan, Ahmet Akıcı, Kemal Berkman, Başak Dönertaş, Sinem Ezgi Gülmez, İbrahim Topcu, Hüseyin Yılmaz
Format: Article
Language:English
Published: Galenos Publishing House 2013-03-01
Series:Balkan Medical Journal
Online Access:http://balkanmedicaljournal.org/text.php?lang=en&id=421
_version_ 1797922884055728128
author Dilek Demircan
Ahmet Akıcı
Kemal Berkman
Başak Dönertaş
Sinem Ezgi Gülmez
İbrahim Topcu
Hüseyin Yılmaz
author_facet Dilek Demircan
Ahmet Akıcı
Kemal Berkman
Başak Dönertaş
Sinem Ezgi Gülmez
İbrahim Topcu
Hüseyin Yılmaz
author_sort Dilek Demircan
collection DOAJ
description Objective: Use of drugs that may lead to abuse or dependence are subject to controlled prescriptions (CPs) in many countries, and these are closely monitored by health authorities. According to national regulations in Turkey, CPs may be red coloured (RCPs) or green coloured (GCPs). The aim of this study was to evaluate the use of such drugs in Istanbul. Study Design: Retrospective case-control study. Material and Methods: During the study period (01/01-31/12 2009), 502874 CPs were reported. Among these, 4000 CPs each month were randomly selected and evaluated. Results: The majority of GCPs were issued to women (55.6%), while the majority of RCPs were issued to men (68.4%). GCPs were most frequently prescribed by physicians working in private hospitals (33.6%) while RCPs by physicians working in university hospitals (39.7%). GCPs were mostly prescribed by psychiatrists (37.6%) while for RCPs were child and adolescent psychiatrists (35.9%). Psycholeptics (ATC code N05) were the most prescribed controlled drugs (CDs) (43.8%). Methylphenidate (53.9%) was the mostly prescribed on RCPs and alprazolam (39.6%) was on GCPs. Conclusion: We demonstrate that utilization of CDs shows demographical and institutional differences. These data could be of help to improve surveillance of CDs as well as to train prescribers and patients.
first_indexed 2024-04-10T14:38:16Z
format Article
id doaj.art-6a7df267c78d4d998f9cd26b4d5092dd
institution Directory Open Access Journal
issn 2146-3123
2146-3131
language English
last_indexed 2024-04-10T14:38:16Z
publishDate 2013-03-01
publisher Galenos Publishing House
record_format Article
series Balkan Medical Journal
spelling doaj.art-6a7df267c78d4d998f9cd26b4d5092dd2023-02-15T16:08:20ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312013-03-01301465310.5152/balkanmedj.2012.073Use of Drugs Subject to Controlled Prescriptions: a Retrospective AnalysisDilek Demircan0Ahmet Akıcı1Kemal Berkman2Başak Dönertaş3Sinem Ezgi Gülmez4İbrahim Topcu5Hüseyin Yılmaz6Department of Pharmacology, Faculty of Medicine, Marmara University, İstanbul, TurkeyDepartment of Pharmacology, Faculty of Medicine, Marmara University, İstanbul, TurkeyDepartment of Pharmacology, Faculty of Medicine, Marmara University, İstanbul, TurkeyDepartment of Pharmacology, Faculty of Medicine, Marmara University, İstanbul, TurkeyINSERM CIC-P 0005 Pharmacoépidémiologie, Service de Pharmacologie, Université Bordeaux Segalen, Bordeaux, FrancePublic Health Directorate of İstanbul, İstanbul, TurkeyProvincial Health Directorate of İstanbul, İstanbul, TurkeyObjective: Use of drugs that may lead to abuse or dependence are subject to controlled prescriptions (CPs) in many countries, and these are closely monitored by health authorities. According to national regulations in Turkey, CPs may be red coloured (RCPs) or green coloured (GCPs). The aim of this study was to evaluate the use of such drugs in Istanbul. Study Design: Retrospective case-control study. Material and Methods: During the study period (01/01-31/12 2009), 502874 CPs were reported. Among these, 4000 CPs each month were randomly selected and evaluated. Results: The majority of GCPs were issued to women (55.6%), while the majority of RCPs were issued to men (68.4%). GCPs were most frequently prescribed by physicians working in private hospitals (33.6%) while RCPs by physicians working in university hospitals (39.7%). GCPs were mostly prescribed by psychiatrists (37.6%) while for RCPs were child and adolescent psychiatrists (35.9%). Psycholeptics (ATC code N05) were the most prescribed controlled drugs (CDs) (43.8%). Methylphenidate (53.9%) was the mostly prescribed on RCPs and alprazolam (39.6%) was on GCPs. Conclusion: We demonstrate that utilization of CDs shows demographical and institutional differences. These data could be of help to improve surveillance of CDs as well as to train prescribers and patients.http://balkanmedicaljournal.org/text.php?lang=en&id=421
spellingShingle Dilek Demircan
Ahmet Akıcı
Kemal Berkman
Başak Dönertaş
Sinem Ezgi Gülmez
İbrahim Topcu
Hüseyin Yılmaz
Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
Balkan Medical Journal
title Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
title_full Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
title_fullStr Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
title_full_unstemmed Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
title_short Use of Drugs Subject to Controlled Prescriptions: a Retrospective Analysis
title_sort use of drugs subject to controlled prescriptions a retrospective analysis
url http://balkanmedicaljournal.org/text.php?lang=en&id=421
work_keys_str_mv AT dilekdemircan useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT ahmetakıcı useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT kemalberkman useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT basakdonertas useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT sinemezgigulmez useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT ibrahimtopcu useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis
AT huseyinyılmaz useofdrugssubjecttocontrolledprescriptionsaretrospectiveanalysis