Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms

Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that...

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Main Authors: Panthakarn Rangsinth, Rajasekharan Sharika, Nattaporn Pattarachotanant, Chatrawee Duangjan, Chamaiphron Wongwan, Chanin Sillapachaiyaporn, Sunita Nilkhet, Nichaporn Wongsirojkul, Anchalee Prasansuklab, Tewin Tencomnao, George Pak-Heng Leung, Siriporn Chuchawankul
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/12/13/2529
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author Panthakarn Rangsinth
Rajasekharan Sharika
Nattaporn Pattarachotanant
Chatrawee Duangjan
Chamaiphron Wongwan
Chanin Sillapachaiyaporn
Sunita Nilkhet
Nichaporn Wongsirojkul
Anchalee Prasansuklab
Tewin Tencomnao
George Pak-Heng Leung
Siriporn Chuchawankul
author_facet Panthakarn Rangsinth
Rajasekharan Sharika
Nattaporn Pattarachotanant
Chatrawee Duangjan
Chamaiphron Wongwan
Chanin Sillapachaiyaporn
Sunita Nilkhet
Nichaporn Wongsirojkul
Anchalee Prasansuklab
Tewin Tencomnao
George Pak-Heng Leung
Siriporn Chuchawankul
author_sort Panthakarn Rangsinth
collection DOAJ
description Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.
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spelling doaj.art-6a80e747f4194637adf87631c6629db42023-11-18T16:33:50ZengMDPI AGFoods2304-81582023-06-011213252910.3390/foods12132529Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible MushroomsPanthakarn Rangsinth0Rajasekharan Sharika1Nattaporn Pattarachotanant2Chatrawee Duangjan3Chamaiphron Wongwan4Chanin Sillapachaiyaporn5Sunita Nilkhet6Nichaporn Wongsirojkul7Anchalee Prasansuklab8Tewin Tencomnao9George Pak-Heng Leung10Siriporn Chuchawankul11Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USADepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandCollege of Public Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Pokfulam, Hong Kong SAR, ChinaDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandErgosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.https://www.mdpi.com/2304-8158/12/13/2529ergosterolnutritionfood chemistrybioactive compoundnutraceutical
spellingShingle Panthakarn Rangsinth
Rajasekharan Sharika
Nattaporn Pattarachotanant
Chatrawee Duangjan
Chamaiphron Wongwan
Chanin Sillapachaiyaporn
Sunita Nilkhet
Nichaporn Wongsirojkul
Anchalee Prasansuklab
Tewin Tencomnao
George Pak-Heng Leung
Siriporn Chuchawankul
Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
Foods
ergosterol
nutrition
food chemistry
bioactive compound
nutraceutical
title Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
title_full Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
title_fullStr Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
title_full_unstemmed Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
title_short Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
title_sort potential beneficial effects and pharmacological properties of ergosterol a common bioactive compound in edible mushrooms
topic ergosterol
nutrition
food chemistry
bioactive compound
nutraceutical
url https://www.mdpi.com/2304-8158/12/13/2529
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