Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms
Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that...
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MDPI AG
2023-06-01
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author | Panthakarn Rangsinth Rajasekharan Sharika Nattaporn Pattarachotanant Chatrawee Duangjan Chamaiphron Wongwan Chanin Sillapachaiyaporn Sunita Nilkhet Nichaporn Wongsirojkul Anchalee Prasansuklab Tewin Tencomnao George Pak-Heng Leung Siriporn Chuchawankul |
author_facet | Panthakarn Rangsinth Rajasekharan Sharika Nattaporn Pattarachotanant Chatrawee Duangjan Chamaiphron Wongwan Chanin Sillapachaiyaporn Sunita Nilkhet Nichaporn Wongsirojkul Anchalee Prasansuklab Tewin Tencomnao George Pak-Heng Leung Siriporn Chuchawankul |
author_sort | Panthakarn Rangsinth |
collection | DOAJ |
description | Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed. |
first_indexed | 2024-03-11T01:41:05Z |
format | Article |
id | doaj.art-6a80e747f4194637adf87631c6629db4 |
institution | Directory Open Access Journal |
issn | 2304-8158 |
language | English |
last_indexed | 2024-03-11T01:41:05Z |
publishDate | 2023-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Foods |
spelling | doaj.art-6a80e747f4194637adf87631c6629db42023-11-18T16:33:50ZengMDPI AGFoods2304-81582023-06-011213252910.3390/foods12132529Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible MushroomsPanthakarn Rangsinth0Rajasekharan Sharika1Nattaporn Pattarachotanant2Chatrawee Duangjan3Chamaiphron Wongwan4Chanin Sillapachaiyaporn5Sunita Nilkhet6Nichaporn Wongsirojkul7Anchalee Prasansuklab8Tewin Tencomnao9George Pak-Heng Leung10Siriporn Chuchawankul11Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USADepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandCollege of Public Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Pokfulam, Hong Kong SAR, ChinaDepartment of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandErgosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.https://www.mdpi.com/2304-8158/12/13/2529ergosterolnutritionfood chemistrybioactive compoundnutraceutical |
spellingShingle | Panthakarn Rangsinth Rajasekharan Sharika Nattaporn Pattarachotanant Chatrawee Duangjan Chamaiphron Wongwan Chanin Sillapachaiyaporn Sunita Nilkhet Nichaporn Wongsirojkul Anchalee Prasansuklab Tewin Tencomnao George Pak-Heng Leung Siriporn Chuchawankul Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms Foods ergosterol nutrition food chemistry bioactive compound nutraceutical |
title | Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms |
title_full | Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms |
title_fullStr | Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms |
title_full_unstemmed | Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms |
title_short | Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms |
title_sort | potential beneficial effects and pharmacological properties of ergosterol a common bioactive compound in edible mushrooms |
topic | ergosterol nutrition food chemistry bioactive compound nutraceutical |
url | https://www.mdpi.com/2304-8158/12/13/2529 |
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