Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies

Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies

Background Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 (TsT26) enables the detection of low-frequency variants across 26 genes using the...

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Bibliographic Details
Main Authors: Iván Prieto-Potin, Nerea Carvajal, Jenifer Plaza-Sánchez, Rebeca Manso, Carmen Laura Aúz-Alexandre, Cristina Chamizo, Sandra Zazo, Almudena López-Sánchez, Socorro María Rodríguez-Pinilla, Laura Camacho, Raquel Longarón, Beatriz Bellosillo, Rosa Somoza, Javier Hernández-Losa, Víctor Manuel Fernández-Soria, Ricardo Ramos-Ruiz, Ion Cristóbal, Jesús García-Foncillas, Federico Rojo
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Next-generation sequencing
Validation
Cancer
Solid tumor
Hematological malignancies
Online Access:https://peerj.com/articles/10069.pdf

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