Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice

Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice

Abstract Background N-acetylneuraminic acid (NANA) is the major form of sialic acid in mammals, and the plasma NANA level is increased in patients with cardiovascular diseases. Exogenous supplement of NANA has been demonstrated to reduce hyperlipidaemia and the formation of atherosclerotic lesions;...

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Bibliographic Details
Main Authors: Pengbo Hou, Shumei Hu, Jin Wang, Zixun Yang, Jiayu Yin, Guanghai Zhou, Shoudong Guo
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Lipids in Health and Disease
Subjects:
Istope tracing; sialic acid
Atherosclerosis
High-fat diet
Online Access:http://link.springer.com/article/10.1186/s12944-019-0971-1

Internet

http://link.springer.com/article/10.1186/s12944-019-0971-1

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