ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
Over the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look...
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Format: | Article |
Language: | English |
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MDPI AG
2021-06-01
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Series: | Diagnostics |
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Online Access: | https://www.mdpi.com/2075-4418/11/7/1189 |
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author | Peter M. A. Calverley Paul Phillip Walker |
author_facet | Peter M. A. Calverley Paul Phillip Walker |
author_sort | Peter M. A. Calverley |
collection | DOAJ |
description | Over the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look at pathological and physiological features along with symptoms and consider the impact of each diagnosis upon therapeutic management. We highlight challenges in the diagnosis and management of airway disease and the various phenotypes that could be part of ACO, in so doing suggesting ways for the clinician to manage patients with features of both asthma and COPD. |
first_indexed | 2024-03-09T04:44:56Z |
format | Article |
id | doaj.art-6a84d716c34c4f7784b3f020f7eb4738 |
institution | Directory Open Access Journal |
issn | 2075-4418 |
language | English |
last_indexed | 2024-03-09T04:44:56Z |
publishDate | 2021-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Diagnostics |
spelling | doaj.art-6a84d716c34c4f7784b3f020f7eb47382023-12-03T13:17:07ZengMDPI AGDiagnostics2075-44182021-06-01117118910.3390/diagnostics11071189ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case AgainstPeter M. A. Calverley0Paul Phillip Walker1Department of Clinical Science, University of Liverpool, Liverpool L9 7AL, UKLiverpool University Hospitals Foundation NHS, University of Liverpool, Liverpool L9 7AL, UKOver the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look at pathological and physiological features along with symptoms and consider the impact of each diagnosis upon therapeutic management. We highlight challenges in the diagnosis and management of airway disease and the various phenotypes that could be part of ACO, in so doing suggesting ways for the clinician to manage patients with features of both asthma and COPD.https://www.mdpi.com/2075-4418/11/7/1189COPDasthmaasthma–COPD overlaprespiratory pathophysiologybronchodilator reversibility |
spellingShingle | Peter M. A. Calverley Paul Phillip Walker ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against Diagnostics COPD asthma asthma–COPD overlap respiratory pathophysiology bronchodilator reversibility |
title | ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against |
title_full | ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against |
title_fullStr | ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against |
title_full_unstemmed | ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against |
title_short | ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against |
title_sort | aco asthma copd overlap is independent from copd the case against |
topic | COPD asthma asthma–COPD overlap respiratory pathophysiology bronchodilator reversibility |
url | https://www.mdpi.com/2075-4418/11/7/1189 |
work_keys_str_mv | AT petermacalverley acoasthmacopdoverlapisindependentfromcopdthecaseagainst AT paulphillipwalker acoasthmacopdoverlapisindependentfromcopdthecaseagainst |