ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against

Over the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look...

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Main Authors: Peter M. A. Calverley, Paul Phillip Walker
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/7/1189
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author Peter M. A. Calverley
Paul Phillip Walker
author_facet Peter M. A. Calverley
Paul Phillip Walker
author_sort Peter M. A. Calverley
collection DOAJ
description Over the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look at pathological and physiological features along with symptoms and consider the impact of each diagnosis upon therapeutic management. We highlight challenges in the diagnosis and management of airway disease and the various phenotypes that could be part of ACO, in so doing suggesting ways for the clinician to manage patients with features of both asthma and COPD.
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spelling doaj.art-6a84d716c34c4f7784b3f020f7eb47382023-12-03T13:17:07ZengMDPI AGDiagnostics2075-44182021-06-01117118910.3390/diagnostics11071189ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case AgainstPeter M. A. Calverley0Paul Phillip Walker1Department of Clinical Science, University of Liverpool, Liverpool L9 7AL, UKLiverpool University Hospitals Foundation NHS, University of Liverpool, Liverpool L9 7AL, UKOver the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look at pathological and physiological features along with symptoms and consider the impact of each diagnosis upon therapeutic management. We highlight challenges in the diagnosis and management of airway disease and the various phenotypes that could be part of ACO, in so doing suggesting ways for the clinician to manage patients with features of both asthma and COPD.https://www.mdpi.com/2075-4418/11/7/1189COPDasthmaasthma–COPD overlaprespiratory pathophysiologybronchodilator reversibility
spellingShingle Peter M. A. Calverley
Paul Phillip Walker
ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
Diagnostics
COPD
asthma
asthma–COPD overlap
respiratory pathophysiology
bronchodilator reversibility
title ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
title_full ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
title_fullStr ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
title_full_unstemmed ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
title_short ACO (Asthma–COPD Overlap) Is Independent from COPD: The Case Against
title_sort aco asthma copd overlap is independent from copd the case against
topic COPD
asthma
asthma–COPD overlap
respiratory pathophysiology
bronchodilator reversibility
url https://www.mdpi.com/2075-4418/11/7/1189
work_keys_str_mv AT petermacalverley acoasthmacopdoverlapisindependentfromcopdthecaseagainst
AT paulphillipwalker acoasthmacopdoverlapisindependentfromcopdthecaseagainst