First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report
Background: Embryo selection is a vital part of in vitro fertilization (IVF) programs, with morphology-based grading systems having been widely used for decades. Time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. We report the firs...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Shahid Sadoughi University of Medical Science, Yazd, Iran
2015-03-01
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| Series: | Iranian Journal of Reproductive Medicine |
| Online Access: | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1476/840 |
| _version_ | 1811313727405817856 |
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| author | Azita Faramarzi Mohammad Ali Khalili Mehrdad Soleimani |
| author_facet | Azita Faramarzi Mohammad Ali Khalili Mehrdad Soleimani |
| author_sort | Azita Faramarzi |
| collection | DOAJ |
| description | Background: Embryo selection is a vital part of in vitro fertilization (IVF) programs, with morphology-based grading systems having been widely used for decades. Time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. We report the first ongoing and chemical pregnancies using Time-lapse embryo scope to select best embryos for transfer in Iran.
Cases: A case with tubal factor infertility was admitted to IVF program with normozoospermia. After ovarian hyper stimulation, 6 COCs were retrieved and inseminated with 25,000 progressive sperms/ oocyte. Five zygotes were placed individually into the micro wells of equilibrated embryo scope dish for Time-lapse observation, and incubated at 37°C, 5% CO2. On day 3, single embryo transfer (SET) took place based on kinetic parameters of the embryos. Clinical pregnancy was confirmed 7 weeks after SET. The second case with history of previous ICSI failure was admitted with azoospermia. Nine MII oocytes underwent ICSI, and incubated in Time-lapse facilities. The rest of procedures were followed as described for case 1. Chemical pregnancy was confirmed 15 days after SET.
Conclusion: This approach opens a way to select best embryo non-invasively for SET; thus, increasing implantation, while reducing multiple pregnancy complications. |
| first_indexed | 2024-04-13T10:59:54Z |
| format | Article |
| id | doaj.art-6a86ec21b2e343858366d41946d42560 |
| institution | Directory Open Access Journal |
| issn | 1680-6433 2008-2177 |
| language | English |
| last_indexed | 2024-04-13T10:59:54Z |
| publishDate | 2015-03-01 |
| publisher | Shahid Sadoughi University of Medical Science, Yazd, Iran |
| record_format | Article |
| series | Iranian Journal of Reproductive Medicine |
| spelling | doaj.art-6a86ec21b2e343858366d41946d425602022-12-22T02:49:26ZengShahid Sadoughi University of Medical Science, Yazd, IranIranian Journal of Reproductive Medicine1680-64332008-21772015-03-01134237242First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case reportAzita Faramarzi0Mohammad Ali Khalili 1Mehrdad Soleimani 2Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Background: Embryo selection is a vital part of in vitro fertilization (IVF) programs, with morphology-based grading systems having been widely used for decades. Time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. We report the first ongoing and chemical pregnancies using Time-lapse embryo scope to select best embryos for transfer in Iran. Cases: A case with tubal factor infertility was admitted to IVF program with normozoospermia. After ovarian hyper stimulation, 6 COCs were retrieved and inseminated with 25,000 progressive sperms/ oocyte. Five zygotes were placed individually into the micro wells of equilibrated embryo scope dish for Time-lapse observation, and incubated at 37°C, 5% CO2. On day 3, single embryo transfer (SET) took place based on kinetic parameters of the embryos. Clinical pregnancy was confirmed 7 weeks after SET. The second case with history of previous ICSI failure was admitted with azoospermia. Nine MII oocytes underwent ICSI, and incubated in Time-lapse facilities. The rest of procedures were followed as described for case 1. Chemical pregnancy was confirmed 15 days after SET. Conclusion: This approach opens a way to select best embryo non-invasively for SET; thus, increasing implantation, while reducing multiple pregnancy complications.http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1476/840 |
| spellingShingle | Azita Faramarzi Mohammad Ali Khalili Mehrdad Soleimani First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report Iranian Journal of Reproductive Medicine |
| title | First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report |
| title_full | First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report |
| title_fullStr | First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report |
| title_full_unstemmed | First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report |
| title_short | First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report |
| title_sort | first successful pregnancies following embryo selection using time lapse technology in iran case report |
| url | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1476/840 |
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