Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications
The development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/22/12294 |
| _version_ | 1797509996570738688 |
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| author | Athandwe M. Paca Peter A. Ajibade |
| author_facet | Athandwe M. Paca Peter A. Ajibade |
| author_sort | Athandwe M. Paca |
| collection | DOAJ |
| description | The development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically impossible to accomplish using larger molecules or bulk materials. Fabrication of nanomaterials is the most effective platform to engineer therapeutic agents and delivery systems for the treatment of cancer. This is mostly due to the high selectivity of nanomaterials for cancerous cells, which is attributable to the porous morphology of tumour cells which allows nanomaterials to accumulate more in tumour cells more than in normal cells. Nanomaterials can be used as potential drug delivery systems since they exist in similar scale as proteins. The unique properties of nanomaterials have drawn a lot of interest from researchers in search of new chemotherapeutic treatment for cancer. Metal sulfide nanomaterials have emerged as the most used frameworks in the past decade, but they tend to aggregate because of their high surface energy which triggers the thermodynamically favoured interaction. Stabilizing agents such as polymer and microgels have been utilized to inhibit the particles from any aggregations. In this review, we explore the development of metal sulfide polymer/microgel nanocomposites as therapeutic agents against cancerous cells. |
| first_indexed | 2024-03-10T05:25:39Z |
| format | Article |
| id | doaj.art-6a8826928a404491b11844c4e25bb82e |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T05:25:39Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-6a8826928a404491b11844c4e25bb82e2023-11-22T23:40:04ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-11-0122221229410.3390/ijms222212294Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical ApplicationsAthandwe M. Paca0Peter A. Ajibade1School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg 3209, South AfricaSchool of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg 3209, South AfricaThe development of nanomaterials with therapeutic and/or diagnostic properties has been an active area of research in biomedical sciences over the past decade. Nanomaterials have been identified as significant medical tools with potential therapeutic and diagnostic capabilities that are practically impossible to accomplish using larger molecules or bulk materials. Fabrication of nanomaterials is the most effective platform to engineer therapeutic agents and delivery systems for the treatment of cancer. This is mostly due to the high selectivity of nanomaterials for cancerous cells, which is attributable to the porous morphology of tumour cells which allows nanomaterials to accumulate more in tumour cells more than in normal cells. Nanomaterials can be used as potential drug delivery systems since they exist in similar scale as proteins. The unique properties of nanomaterials have drawn a lot of interest from researchers in search of new chemotherapeutic treatment for cancer. Metal sulfide nanomaterials have emerged as the most used frameworks in the past decade, but they tend to aggregate because of their high surface energy which triggers the thermodynamically favoured interaction. Stabilizing agents such as polymer and microgels have been utilized to inhibit the particles from any aggregations. In this review, we explore the development of metal sulfide polymer/microgel nanocomposites as therapeutic agents against cancerous cells.https://www.mdpi.com/1422-0067/22/22/12294semiconductor nanomaterialsmetal sulfidetherapeutic agentsdrug deliverypolymer microgels |
| spellingShingle | Athandwe M. Paca Peter A. Ajibade Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications International Journal of Molecular Sciences semiconductor nanomaterials metal sulfide therapeutic agents drug delivery polymer microgels |
| title | Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications |
| title_full | Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications |
| title_fullStr | Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications |
| title_full_unstemmed | Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications |
| title_short | Metal Sulfide Semiconductor Nanomaterials and Polymer Microgels for Biomedical Applications |
| title_sort | metal sulfide semiconductor nanomaterials and polymer microgels for biomedical applications |
| topic | semiconductor nanomaterials metal sulfide therapeutic agents drug delivery polymer microgels |
| url | https://www.mdpi.com/1422-0067/22/22/12294 |
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