Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia
INTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
2010-01-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000900004 |
| _version_ | 1811330582065446912 |
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| author | José Luiz Orlando Jose Guilherme Mendes Pereira Caldas Heloisa Galvão do Amaral Campos Kenji Nishinari Nelson Wolosker |
| author_facet | José Luiz Orlando Jose Guilherme Mendes Pereira Caldas Heloisa Galvão do Amaral Campos Kenji Nishinari Nelson Wolosker |
| author_sort | José Luiz Orlando |
| collection | DOAJ |
| description | INTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze the results of treating Deep venous malformations patients with low doses of ethanol. METHODS: Thirty-nine patients treated between July 1995 and June 2007 were followed up prospectively over a median period of 18 months. Twenty-nine were female (74.4%) and 10 were male (25.6%), with ages ranging from 11 to 59 years (median of 24 years). All of the lesions affected limbs, and the main symptom reported was pain (97.4%). Each patient underwent fortnightly alcohol application sessions under local anesthesia on an outpatient basis. The lesions were classified into three groups according to size using nuclear magnetic resonance imaging: small, up to 3 cm (4 patients); medium, between 3 and 15 cm (27 patients); and large, greater than 15 cm (8 patients). RESULTS: The symptoms completely disappeared in 14 patients (35.9%) and improved in 24 (61.5%). The lesion size reduced to zero in 6 patients (15.4%) and decreased in 32 (82%). The median number of sessions was 7. There were no complications in 32 patients (82%), while 3 presented local paresthesia (7.7%), 2 superficial trombophlebites (5.1%), 1 skin ulcer (2.6%), and 1 case of hyperpigmentation (2.6%). CONCLUSION: Outpatient treatment for Deep venous malformations patients using ethanol at low doses was effective, with a low complication rate. |
| first_indexed | 2024-04-13T16:05:37Z |
| format | Article |
| id | doaj.art-6a8c75da4f394e339a2008150ddca7cb |
| institution | Directory Open Access Journal |
| issn | 1807-5932 1980-5322 |
| language | English |
| last_indexed | 2024-04-13T16:05:37Z |
| publishDate | 2010-01-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-6a8c75da4f394e339a2008150ddca7cb2022-12-22T02:40:24ZengElsevier EspañaClinics1807-59321980-53222010-01-0165983784010.1590/S1807-59322010000900004Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesiaJosé Luiz OrlandoJose Guilherme Mendes Pereira CaldasHeloisa Galvão do Amaral CamposKenji NishinariNelson WoloskerINTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze the results of treating Deep venous malformations patients with low doses of ethanol. METHODS: Thirty-nine patients treated between July 1995 and June 2007 were followed up prospectively over a median period of 18 months. Twenty-nine were female (74.4%) and 10 were male (25.6%), with ages ranging from 11 to 59 years (median of 24 years). All of the lesions affected limbs, and the main symptom reported was pain (97.4%). Each patient underwent fortnightly alcohol application sessions under local anesthesia on an outpatient basis. The lesions were classified into three groups according to size using nuclear magnetic resonance imaging: small, up to 3 cm (4 patients); medium, between 3 and 15 cm (27 patients); and large, greater than 15 cm (8 patients). RESULTS: The symptoms completely disappeared in 14 patients (35.9%) and improved in 24 (61.5%). The lesion size reduced to zero in 6 patients (15.4%) and decreased in 32 (82%). The median number of sessions was 7. There were no complications in 32 patients (82%), while 3 presented local paresthesia (7.7%), 2 superficial trombophlebites (5.1%), 1 skin ulcer (2.6%), and 1 case of hyperpigmentation (2.6%). CONCLUSION: Outpatient treatment for Deep venous malformations patients using ethanol at low doses was effective, with a low complication rate.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000900004Venous malformationsPercutaneousSclerotherapyEthanolLocal anesthesia |
| spellingShingle | José Luiz Orlando Jose Guilherme Mendes Pereira Caldas Heloisa Galvão do Amaral Campos Kenji Nishinari Nelson Wolosker Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia Clinics Venous malformations Percutaneous Sclerotherapy Ethanol Local anesthesia |
| title | Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| title_full | Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| title_fullStr | Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| title_full_unstemmed | Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| title_short | Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| title_sort | outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
| topic | Venous malformations Percutaneous Sclerotherapy Ethanol Local anesthesia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000900004 |
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