Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection
Immune, neuroendocrine, and autonomic nervous system dysregulation in anorexia nervosa lead to cardiovascular complications that can potentially result in increased morbidity and mortality. It is suggested that a complex non-invasive assessment of cardiovascular autonomic regulation—cardiac vagal co...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/9/5043 |
| _version_ | 1797534733911982080 |
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| author | Maria Maddalena Sirufo Lia Ginaldi Massimo De Martinis |
| author_facet | Maria Maddalena Sirufo Lia Ginaldi Massimo De Martinis |
| author_sort | Maria Maddalena Sirufo |
| collection | DOAJ |
| description | Immune, neuroendocrine, and autonomic nervous system dysregulation in anorexia nervosa lead to cardiovascular complications that can potentially result in increased morbidity and mortality. It is suggested that a complex non-invasive assessment of cardiovascular autonomic regulation—cardiac vagal control, sympathetic vascular activity, and cardiovascular reflex control—could represent a promising tool for early diagnosis, personalized therapy, and monitoring of therapeutic interventions in anorexia nervosa particularly at a vulnerable adolescent age. In this view, we recommend to consider in the diagnostic route, at least in the subset of patients with peripheral microvascular symptoms, a nailfold video-capillaroscopy as an easy not invasive tool for the early assessing of possible cardiovascular involvement. |
| first_indexed | 2024-03-10T11:34:38Z |
| format | Article |
| id | doaj.art-6a8e2b85e7bb4de5b8eba9dbfa6a56cb |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T11:34:38Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-6a8e2b85e7bb4de5b8eba9dbfa6a56cb2023-11-21T19:00:35ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-05-01229504310.3390/ijms22095043Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic ConnectionMaria Maddalena Sirufo0Lia Ginaldi1Massimo De Martinis2Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyImmune, neuroendocrine, and autonomic nervous system dysregulation in anorexia nervosa lead to cardiovascular complications that can potentially result in increased morbidity and mortality. It is suggested that a complex non-invasive assessment of cardiovascular autonomic regulation—cardiac vagal control, sympathetic vascular activity, and cardiovascular reflex control—could represent a promising tool for early diagnosis, personalized therapy, and monitoring of therapeutic interventions in anorexia nervosa particularly at a vulnerable adolescent age. In this view, we recommend to consider in the diagnostic route, at least in the subset of patients with peripheral microvascular symptoms, a nailfold video-capillaroscopy as an easy not invasive tool for the early assessing of possible cardiovascular involvement.https://www.mdpi.com/1422-0067/22/9/5043anorexia nervosaneuroendocrine dysregulationcytokinescardiovascular diseasescapillaroscopynailfoldcapillaroscopy |
| spellingShingle | Maria Maddalena Sirufo Lia Ginaldi Massimo De Martinis Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection International Journal of Molecular Sciences anorexia nervosa neuroendocrine dysregulation cytokines cardiovascular diseases capillaroscopy nailfoldcapillaroscopy |
| title | Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection |
| title_full | Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection |
| title_fullStr | Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection |
| title_full_unstemmed | Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection |
| title_short | Peripheral Vascular Abnormalities in Anorexia Nervosa: A Psycho-Neuro-Immune-Metabolic Connection |
| title_sort | peripheral vascular abnormalities in anorexia nervosa a psycho neuro immune metabolic connection |
| topic | anorexia nervosa neuroendocrine dysregulation cytokines cardiovascular diseases capillaroscopy nailfoldcapillaroscopy |
| url | https://www.mdpi.com/1422-0067/22/9/5043 |
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