4,5-Dimethoxy-2-nitrobenzohydrazides and 1-(1-Benzylpiperidin-4-yl)ethan-1-ones as Potential Antioxidant/Cholinergic Endowed Small Molecule Leads

4,5-Dimethoxy-2-nitrobenzohydrazides and 1-(1-Benzylpiperidin-4-yl)ethan-1-ones as Potential Antioxidant/Cholinergic Endowed Small Molecule Leads

The objective of this research is to generate leads for developing our ultimate poly-active molecules with utility in central nervous system (CNS) diseases. Indeed, poly-active molecules capable of mitigating brain free radical damage while enhancing acetylcholine signaling (via cholinesterase inhib...

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Bibliographic Details
Main Authors: Rukhsar Banu, Jason Gerding, Cynthia Franklin, Donald Sikazwe, William Horton, Marianna Török, Julian Davis, Kwan H. Cheng, Muziya Nakazwe, Bereket Mochona
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Scientia Pharmaceutica
Subjects:
poly-active
antioxidant
hydrazones
isonipecotates
cholinesterase
in silico
Online Access:https://www.mdpi.com/2218-0532/86/1/2

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