Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population
Abstract Background To investigate the associations between anterior segment biometry and high axial myopia in cataractous eyes in the Chinese population. Methods Data on 3438 eyes from 3438 subjects were analyzed in this cross-sectional study. Anterior segment biometry, axial length measurements, a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02300-6 |
| _version_ | 1819274296325832704 |
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| author | Ao Miao Yating Tang Xiangjia Zhu Dongjin Qian Tianyu Zheng Yi Lu |
| author_facet | Ao Miao Yating Tang Xiangjia Zhu Dongjin Qian Tianyu Zheng Yi Lu |
| author_sort | Ao Miao |
| collection | DOAJ |
| description | Abstract Background To investigate the associations between anterior segment biometry and high axial myopia in cataractous eyes in the Chinese population. Methods Data on 3438 eyes from 3438 subjects were analyzed in this cross-sectional study. Anterior segment biometry, axial length measurements, and intraocular pressure evaluation were implemented using an Oculus Pentacam HR, a Zeiss IOLMaster 500, and a Nidek TonoRef II, respectively. A multivariate-adjusted logistic model and a multivariate-adjusted linear model were used for statistical analysis. Results The mean age of the subjects was 62.2 ± 10.6 years, and 56.4% were female. There were 2665 subjects with high axial myopia (axial length, ≥26.50 mm) and 773 without (axial length, < 26.50 mm). The characteristics independently associated with high axial myopia included lower total corneal refractive power, a more negative Q value, greater total corneal astigmatism, greater white-to-white corneal diameter, greater anterior chamber depth, and higher intraocular pressure (all P < 0.05). In addition, greater axial length correlated with a thicker temporal cornea and a thinner nasal cornea (both P < 0.001). Conclusions For cataractous eyes, high axial myopia was associated with corneal flattening, increased total corneal astigmatism, anterior segment enlargement, and intraocular pressure elevation. The findings may inform the choice of intraocular lenses and the calculation of their power, help improve the surgical practice of refractive cataract procedures, and provide useful information on the centration and stability of intraocular lenses. |
| first_indexed | 2024-12-23T23:06:10Z |
| format | Article |
| id | doaj.art-6a945b3654264297a6bc457e60d3806f |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-23T23:06:10Z |
| publishDate | 2022-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-6a945b3654264297a6bc457e60d3806f2022-12-21T17:26:48ZengBMCBMC Ophthalmology1471-24152022-02-0122111210.1186/s12886-022-02300-6Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese populationAo Miao0Yating Tang1Xiangjia Zhu2Dongjin Qian3Tianyu Zheng4Yi Lu5Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical College, Fudan UniversityAbstract Background To investigate the associations between anterior segment biometry and high axial myopia in cataractous eyes in the Chinese population. Methods Data on 3438 eyes from 3438 subjects were analyzed in this cross-sectional study. Anterior segment biometry, axial length measurements, and intraocular pressure evaluation were implemented using an Oculus Pentacam HR, a Zeiss IOLMaster 500, and a Nidek TonoRef II, respectively. A multivariate-adjusted logistic model and a multivariate-adjusted linear model were used for statistical analysis. Results The mean age of the subjects was 62.2 ± 10.6 years, and 56.4% were female. There were 2665 subjects with high axial myopia (axial length, ≥26.50 mm) and 773 without (axial length, < 26.50 mm). The characteristics independently associated with high axial myopia included lower total corneal refractive power, a more negative Q value, greater total corneal astigmatism, greater white-to-white corneal diameter, greater anterior chamber depth, and higher intraocular pressure (all P < 0.05). In addition, greater axial length correlated with a thicker temporal cornea and a thinner nasal cornea (both P < 0.001). Conclusions For cataractous eyes, high axial myopia was associated with corneal flattening, increased total corneal astigmatism, anterior segment enlargement, and intraocular pressure elevation. The findings may inform the choice of intraocular lenses and the calculation of their power, help improve the surgical practice of refractive cataract procedures, and provide useful information on the centration and stability of intraocular lenses.https://doi.org/10.1186/s12886-022-02300-6Anterior eye segmentHigh myopiaOcular biometryCorneal topographyIntraocular pressure |
| spellingShingle | Ao Miao Yating Tang Xiangjia Zhu Dongjin Qian Tianyu Zheng Yi Lu Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population BMC Ophthalmology Anterior eye segment High myopia Ocular biometry Corneal topography Intraocular pressure |
| title | Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population |
| title_full | Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population |
| title_fullStr | Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population |
| title_full_unstemmed | Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population |
| title_short | Associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the Chinese population |
| title_sort | associations between anterior segment biometry and high axial myopia in 3438 cataractous eyes in the chinese population |
| topic | Anterior eye segment High myopia Ocular biometry Corneal topography Intraocular pressure |
| url | https://doi.org/10.1186/s12886-022-02300-6 |
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