Development and Comparison of a Panel of Modified CS17 Fimbrial Tip Adhesin Proteins as Components for an Adhesin-Based Vaccine against Enterotoxigenic <i>Escherichia coli</i>

Development and Comparison of a Panel of Modified CS17 Fimbrial Tip Adhesin Proteins as Components for an Adhesin-Based Vaccine against Enterotoxigenic <i>Escherichia coli</i>

Enterotoxigenic <i>Escherichia coli</i> (ETEC) is a leading cause of diarrhea in travelers and children in resource-limited countries. ETEC colonization factors, fimbrial tip adhesins and enterotoxins are key virulence factors, and thus have been studied as vaccine candidates. Some preva...

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Bibliographic Details
Main Authors: Yang Liu, Milton Maciel, Aisling O’Dowd, Steven T. Poole, Julianne E. Rollenhagen, Irina V. Etobayeva, Stephen J. Savarino
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Microorganisms
Subjects:
CS17 ETEC
CsbD
vaccine
prophylactic
allele matching
protein engineering
Online Access:https://www.mdpi.com/2076-2607/9/8/1646

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