Research hotspots and trends of chordoma: A bibliometric analysis
BackgroundChordoma is a type of mesenchymal malignancy with a high recurrence rate and poor prognosis. Due to its rarity, the tumorigenic mechanism and optimal therapeutic strategy are not well known.MethodsAll relevant articles of chordoma research from 1 January 2000 to 26 April 2022 were obtained...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.946597/full |
| _version_ | 1797995244625592320 |
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| author | Jianxuan Gao Jianxuan Gao Runzhi Huang Huabin Yin Dianwen Song Tong Meng Tong Meng |
| author_facet | Jianxuan Gao Jianxuan Gao Runzhi Huang Huabin Yin Dianwen Song Tong Meng Tong Meng |
| author_sort | Jianxuan Gao |
| collection | DOAJ |
| description | BackgroundChordoma is a type of mesenchymal malignancy with a high recurrence rate and poor prognosis. Due to its rarity, the tumorigenic mechanism and optimal therapeutic strategy are not well known.MethodsAll relevant articles of chordoma research from 1 January 2000 to 26 April 2022 were obtained from Web of Science Core Collection database. Blibliometrix was used to acquire basic publication data. Visualization and data table of collaboration network, dynamic analysis, trend topics, thematic map, and factorial analysis were acquired using Blibliometrix package. VOSviewer was used to generate a visualization map of co-citation analysis and co-occurrence.ResultsA total of 2,285 articles related to chordoma were identified. The most influential and productive country/region was the United States, and Capital Medical University has published the most articles. Among all high-impact authors, Adrienne M. Flanagan had the highest average citation rate. Neurosurgery was the important periodical for chordoma research with the highest total/average citation rate. We focused on four hotspots in recent chordoma research. The research on surgical treatment and radiotherapy was relatively mature. The molecular signaling pathway, targeted therapy and immunotherapy for chordoma are not yet mature, which will be the future trends of chordoma research.ConclusionThis study indicates that chordoma studies are increasing. Surgery and radiotherapy are well reported and always play fundamental roles in chordoma treatment. The molecular signaling pathway, targeted therapy, and immunotherapy of chordoma are the latest research hotspots. |
| first_indexed | 2024-04-11T09:57:15Z |
| format | Article |
| id | doaj.art-6aadee5a6b384ed4878af02f19972def |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-11T09:57:15Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-6aadee5a6b384ed4878af02f19972def2022-12-22T04:30:31ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-09-011210.3389/fonc.2022.946597946597Research hotspots and trends of chordoma: A bibliometric analysisJianxuan Gao0Jianxuan Gao1Runzhi Huang2Huabin Yin3Dianwen Song4Tong Meng5Tong Meng6Department of Spine Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, ChinaTongji University Cancer Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, ChinaDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Tongji University, Shanghai, ChinaDepartment of Spine Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, ChinaDepartment of Spine Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, ChinaDepartment of Spine Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, ChinaTongji University Cancer Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, ChinaBackgroundChordoma is a type of mesenchymal malignancy with a high recurrence rate and poor prognosis. Due to its rarity, the tumorigenic mechanism and optimal therapeutic strategy are not well known.MethodsAll relevant articles of chordoma research from 1 January 2000 to 26 April 2022 were obtained from Web of Science Core Collection database. Blibliometrix was used to acquire basic publication data. Visualization and data table of collaboration network, dynamic analysis, trend topics, thematic map, and factorial analysis were acquired using Blibliometrix package. VOSviewer was used to generate a visualization map of co-citation analysis and co-occurrence.ResultsA total of 2,285 articles related to chordoma were identified. The most influential and productive country/region was the United States, and Capital Medical University has published the most articles. Among all high-impact authors, Adrienne M. Flanagan had the highest average citation rate. Neurosurgery was the important periodical for chordoma research with the highest total/average citation rate. We focused on four hotspots in recent chordoma research. The research on surgical treatment and radiotherapy was relatively mature. The molecular signaling pathway, targeted therapy and immunotherapy for chordoma are not yet mature, which will be the future trends of chordoma research.ConclusionThis study indicates that chordoma studies are increasing. Surgery and radiotherapy are well reported and always play fundamental roles in chordoma treatment. The molecular signaling pathway, targeted therapy, and immunotherapy of chordoma are the latest research hotspots.https://www.frontiersin.org/articles/10.3389/fonc.2022.946597/fullchordomabibliometric analysishotspotstreatmenttumorigenesis |
| spellingShingle | Jianxuan Gao Jianxuan Gao Runzhi Huang Huabin Yin Dianwen Song Tong Meng Tong Meng Research hotspots and trends of chordoma: A bibliometric analysis Frontiers in Oncology chordoma bibliometric analysis hotspots treatment tumorigenesis |
| title | Research hotspots and trends of chordoma: A bibliometric analysis |
| title_full | Research hotspots and trends of chordoma: A bibliometric analysis |
| title_fullStr | Research hotspots and trends of chordoma: A bibliometric analysis |
| title_full_unstemmed | Research hotspots and trends of chordoma: A bibliometric analysis |
| title_short | Research hotspots and trends of chordoma: A bibliometric analysis |
| title_sort | research hotspots and trends of chordoma a bibliometric analysis |
| topic | chordoma bibliometric analysis hotspots treatment tumorigenesis |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.946597/full |
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