Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups

Twenty-five patients with atypical endometrial hyperplasia (AEH) and 90 patients with Stages I-II endometrial cancer (EC) were followed up. The patients’ mean age was 44.3±2.1 years. A control group consisted of 20 healthy women matched for age. Before treatment, the authors determined the blood lev...

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Main Authors: Yu. S. Sidorenko, E.. A Shurygina, O. G. Shishkina, V. V. Gorobtsova
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/84
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author Yu. S. Sidorenko
E.. A Shurygina
O. G. Shishkina
V. V. Gorobtsova
author_facet Yu. S. Sidorenko
E.. A Shurygina
O. G. Shishkina
V. V. Gorobtsova
author_sort Yu. S. Sidorenko
collection DOAJ
description Twenty-five patients with atypical endometrial hyperplasia (AEH) and 90 patients with Stages I-II endometrial cancer (EC) were followed up. The patients’ mean age was 44.3±2.1 years. A control group consisted of 20 healthy women matched for age. Before treatment, the authors determined the blood levels of adrenocorticotropic hormone and cortisol by radiometric assay and the content of daily excreted cortisol, cortisone, tetrahydrocortisol, tetrahydrocortisone, 11-hydroxy-17-ketosteroids, estrone, estradiol, and pregnanediol by the conventional classical studies.The nature of the impaired synthesis and metabolism of sex and adrenocorticoid hormones and their degree have been found to coincide, which suggest that it is expedient to use these findings to form EC risk groups in patients with AEH in the late reproductive period.
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spelling doaj.art-6ab1fd8ec6134a17bc03fa61916eb06c2023-03-13T08:44:32ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0101838710.17650/1994-4098-2012-0-1-83-8799Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groupsYu. S. Sidorenko0E.. A Shurygina1O. G. Shishkina2V. V. Gorobtsova3ФГБУ РНИОИ Минздравсоцразвития России, Ростов-на-ДонуФГБУ РНИОИ Минздравсоцразвития России, Ростов-на-ДонуФГБУ РНИОИ Минздравсоцразвития России, Ростов-на-ДонуФГБУ РНИОИ Минздравсоцразвития России, Ростов-на-ДонуTwenty-five patients with atypical endometrial hyperplasia (AEH) and 90 patients with Stages I-II endometrial cancer (EC) were followed up. The patients’ mean age was 44.3±2.1 years. A control group consisted of 20 healthy women matched for age. Before treatment, the authors determined the blood levels of adrenocorticotropic hormone and cortisol by radiometric assay and the content of daily excreted cortisol, cortisone, tetrahydrocortisol, tetrahydrocortisone, 11-hydroxy-17-ketosteroids, estrone, estradiol, and pregnanediol by the conventional classical studies.The nature of the impaired synthesis and metabolism of sex and adrenocorticoid hormones and their degree have been found to coincide, which suggest that it is expedient to use these findings to form EC risk groups in patients with AEH in the late reproductive period.https://ojrs.abvpress.ru/ojrs/article/view/84атипическая гиперплазия эндометриярак эндометрияэстрогеныкортикостероиды
spellingShingle Yu. S. Sidorenko
E.. A Shurygina
O. G. Shishkina
V. V. Gorobtsova
Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
Опухоли женской репродуктивной системы
атипическая гиперплазия эндометрия
рак эндометрия
эстрогены
кортикостероиды
title Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
title_full Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
title_fullStr Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
title_full_unstemmed Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
title_short Informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
title_sort informative value of some endocrine homeostatic parameters in the formation of endometrial cancer risk groups
topic атипическая гиперплазия эндометрия
рак эндометрия
эстрогены
кортикостероиды
url https://ojrs.abvpress.ru/ojrs/article/view/84
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AT eashurygina informativevalueofsomeendocrinehomeostaticparametersintheformationofendometrialcancerriskgroups
AT ogshishkina informativevalueofsomeendocrinehomeostaticparametersintheformationofendometrialcancerriskgroups
AT vvgorobtsova informativevalueofsomeendocrinehomeostaticparametersintheformationofendometrialcancerriskgroups