Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review
Wound healing refers to the replacement of damaged tissue through strongly coordinated cellular events. The patient’s condition and different types of wounds complicate the already intricate healing process. Conventional wound dressing materials seem to be insufficient to facilitate and support this...
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| Format: | Article |
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MDPI AG
2021-02-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/4/1713 |
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| author | Ilenia De Luca Parisa Pedram Arash Moeini Pierfrancesco Cerruti Gianfranco Peluso Anna Di Salle Natalie Germann |
| author_facet | Ilenia De Luca Parisa Pedram Arash Moeini Pierfrancesco Cerruti Gianfranco Peluso Anna Di Salle Natalie Germann |
| author_sort | Ilenia De Luca |
| collection | DOAJ |
| description | Wound healing refers to the replacement of damaged tissue through strongly coordinated cellular events. The patient’s condition and different types of wounds complicate the already intricate healing process. Conventional wound dressing materials seem to be insufficient to facilitate and support this mechanism. Nanotechnology could provide the physicochemical properties and specific biological responses needed to promote the healing process. For nanoparticulate dressing design, growing interest has focused on natural biopolymers due to their biocompatibility and good adaptability to technological needs. Polysaccharides are the most common natural biopolymers used for wound-healing materials. In particular, alginate and chitosan polymers exhibit intrinsic antibacterial and anti-inflammatory effects, useful for guaranteeing efficient treatment. Recent studies highlight that several natural plant-derived molecules can influence healing stages. In particular, essential oils show excellent antibacterial, antifungal, antioxidant, and anti-inflammatory properties that can be amplified by combining them with nanotechnological strategies. This review summarizes recent studies concerning essential oils as active secondary compounds in polysaccharide-based wound dressings. |
| first_indexed | 2024-03-09T00:52:34Z |
| format | Article |
| id | doaj.art-6ab7991b716942d5a6d15682e6c082bc |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T00:52:34Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-6ab7991b716942d5a6d15682e6c082bc2023-12-11T17:04:30ZengMDPI AGApplied Sciences2076-34172021-02-01114171310.3390/app11041713Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A ReviewIlenia De Luca0Parisa Pedram1Arash Moeini2Pierfrancesco Cerruti3Gianfranco Peluso4Anna Di Salle5Natalie Germann6Elleva Pharma S.R.L. Via Pietro Castellino, 111, 80131 Naples, ItalyDepartment of Chemical, Materials and Industrial Production Engineering, University of Naples Federico II, 80138 Napoli, ItalyFluid Dynamics of Complex Biosystems, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, GermanyInstitute for Polymers, Composites and Biomaterials (IPCB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli, ItalyResearch Institute on Terrestrial Ecosystems (IRET)—CNR, Via Pietro Castellino 111, 80131 Naples, ItalyResearch Institute on Terrestrial Ecosystems (IRET)—CNR, Via Pietro Castellino 111, 80131 Naples, ItalyFluid Dynamics of Complex Biosystems, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, GermanyWound healing refers to the replacement of damaged tissue through strongly coordinated cellular events. The patient’s condition and different types of wounds complicate the already intricate healing process. Conventional wound dressing materials seem to be insufficient to facilitate and support this mechanism. Nanotechnology could provide the physicochemical properties and specific biological responses needed to promote the healing process. For nanoparticulate dressing design, growing interest has focused on natural biopolymers due to their biocompatibility and good adaptability to technological needs. Polysaccharides are the most common natural biopolymers used for wound-healing materials. In particular, alginate and chitosan polymers exhibit intrinsic antibacterial and anti-inflammatory effects, useful for guaranteeing efficient treatment. Recent studies highlight that several natural plant-derived molecules can influence healing stages. In particular, essential oils show excellent antibacterial, antifungal, antioxidant, and anti-inflammatory properties that can be amplified by combining them with nanotechnological strategies. This review summarizes recent studies concerning essential oils as active secondary compounds in polysaccharide-based wound dressings.https://www.mdpi.com/2076-3417/11/4/1713polysaccharideswound dressingessential oilsnanotechnologywound healingantimicrobial |
| spellingShingle | Ilenia De Luca Parisa Pedram Arash Moeini Pierfrancesco Cerruti Gianfranco Peluso Anna Di Salle Natalie Germann Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review Applied Sciences polysaccharides wound dressing essential oils nanotechnology wound healing antimicrobial |
| title | Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review |
| title_full | Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review |
| title_fullStr | Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review |
| title_full_unstemmed | Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review |
| title_short | Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review |
| title_sort | nanotechnology development for formulating essential oils in wound dressing materials to promote the wound healing process a review |
| topic | polysaccharides wound dressing essential oils nanotechnology wound healing antimicrobial |
| url | https://www.mdpi.com/2076-3417/11/4/1713 |
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