New Inhibitors of the Human p300/CBP Acetyltransferase Are Selectively Active against the Arabidopsis HAC Proteins

New Inhibitors of the Human p300/CBP Acetyltransferase Are Selectively Active against the Arabidopsis HAC Proteins

Histone acetyltransferases (HATs) are involved in the epigenetic positive control of gene expression in eukaryotes. CREB-binding proteins (CBP)/p300, a subfamily of highly conserved HATs, have been shown to function as acetylases on both histones and non-histone proteins. In the model plant <i>...

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Bibliographic Details
Main Authors: Chiara Longo, Andrea Lepri, Andrea Paciolla, Antonella Messore, Daniela De Vita, Maria Carmela Bonaccorsi di Patti, Matteo Amadei, Valentina Noemi Madia, Davide Ialongo, Roberto Di Santo, Roberta Costi, Paola Vittorioso
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Arabidopsis thaliana</i>
HAC proteins
p300/CBP inhibitors
Online Access:https://www.mdpi.com/1422-0067/23/18/10446

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