Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study
AIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience. METHODS: A retrospective st...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2018-04-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.cn/en_publish/2018/4/20180423.pdf |
| _version_ | 1818949362949029888 |
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| author | Tharwat H. Mokbel Eman M. El Hefney Sherein M. Hagras Ahmed A. ALNagdy Amani E. Badawi Manal A. Kasem Shereen M. El Shaer |
| author_facet | Tharwat H. Mokbel Eman M. El Hefney Sherein M. Hagras Ahmed A. ALNagdy Amani E. Badawi Manal A. Kasem Shereen M. El Shaer |
| author_sort | Tharwat H. Mokbel |
| collection | DOAJ |
| description | AIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience.
METHODS: A retrospective study in which the medical files of all glaucoma patients <16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed. Collected data included: age, gender, laterality, visual acuity (VA), refraction, intraocular pressure (IOP), corneal diameter, cup-disc ratio, types and number of surgeries and antiglaucomatous drugs (AGD) at the first and last visit. Prevalence of different subtypes was calculated and means of clinical features were compared.
RESULTS: A total of 305 eyes of 207 patients were included classified into 6 groups: primary congenital glaucoma (PCG), juvenile open angle glaucoma (JOAG), glaucoma associated with systemic disease, glaucoma associated with ocular anomalies, acquired glaucoma and glaucoma following cataract surgery. PCG was the predominant type (55.1%) followed by acquired glaucoma (29.5%). Males represented 63.8% of the whole studied patients. Glaucoma associated with ocular anomaly group showed the youngest age at diagnosis (21.9±30.0mo). The shortest corneal diameter was recorded in post cataract group (10.4±0.5 mm). Highest cup-disc ratio was found in the PCG group (P<0.0005). Glaucoma associated with systemic disease presented with the highest baseline IOP (34.5±5.0 mm Hg). All the cases with PCG were treated surgically with 21.8% required more than one surgery. The majority of the patients (74.2%) in the acquired group were treated medically. Combined trabeculotomy-trabeculectomy was the most frequent operation done, accounting for 34.5% of all primary surgeries. Ahmed valve implantation comprised 87% of the secondary surgeries. Acquired glaucoma group had the highest percent of eyes with good final Snellen's VA (69.4%), while glaucoma associated with ocular anomaly group had poorest final VA.
CONCLUSION: PCG is the most prevalent type of childhood glaucoma, followed by acquired glaucoma especially traumatic hyphema. Combined trabeculotomy-trabeculectomy and Ahmed valve implantation are the most common surgical interventions. CGRN classification is found to provide a consensus skeleton and is recommended to be integrated in our routine ongoing clinical practice. |
| first_indexed | 2024-12-20T09:01:30Z |
| format | Article |
| id | doaj.art-6ab7ab4879a24a6eb92f544abffdaf73 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-20T09:01:30Z |
| publishDate | 2018-04-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-6ab7ab4879a24a6eb92f544abffdaf732022-12-21T19:45:50ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982018-04-0111467468010.18240/ijo.2018.04.23Childhood glaucoma profile in Dakahelia, Egypt: a retrospective studyTharwat H. Mokbel0Eman M. El Hefney1Sherein M. Hagras2Ahmed A. ALNagdy3Amani E. Badawi4Manal A. Kasem5Shereen M. El Shaer6Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptMansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptMansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptMansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptMansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptMansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptCommunity and Public Health Department, Faculty of Medicine, Mansoura University, Mansoura 35516, EgyptAIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience. METHODS: A retrospective study in which the medical files of all glaucoma patients <16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed. Collected data included: age, gender, laterality, visual acuity (VA), refraction, intraocular pressure (IOP), corneal diameter, cup-disc ratio, types and number of surgeries and antiglaucomatous drugs (AGD) at the first and last visit. Prevalence of different subtypes was calculated and means of clinical features were compared. RESULTS: A total of 305 eyes of 207 patients were included classified into 6 groups: primary congenital glaucoma (PCG), juvenile open angle glaucoma (JOAG), glaucoma associated with systemic disease, glaucoma associated with ocular anomalies, acquired glaucoma and glaucoma following cataract surgery. PCG was the predominant type (55.1%) followed by acquired glaucoma (29.5%). Males represented 63.8% of the whole studied patients. Glaucoma associated with ocular anomaly group showed the youngest age at diagnosis (21.9±30.0mo). The shortest corneal diameter was recorded in post cataract group (10.4±0.5 mm). Highest cup-disc ratio was found in the PCG group (P<0.0005). Glaucoma associated with systemic disease presented with the highest baseline IOP (34.5±5.0 mm Hg). All the cases with PCG were treated surgically with 21.8% required more than one surgery. The majority of the patients (74.2%) in the acquired group were treated medically. Combined trabeculotomy-trabeculectomy was the most frequent operation done, accounting for 34.5% of all primary surgeries. Ahmed valve implantation comprised 87% of the secondary surgeries. Acquired glaucoma group had the highest percent of eyes with good final Snellen's VA (69.4%), while glaucoma associated with ocular anomaly group had poorest final VA. CONCLUSION: PCG is the most prevalent type of childhood glaucoma, followed by acquired glaucoma especially traumatic hyphema. Combined trabeculotomy-trabeculectomy and Ahmed valve implantation are the most common surgical interventions. CGRN classification is found to provide a consensus skeleton and is recommended to be integrated in our routine ongoing clinical practice.http://www.ijo.cn/en_publish/2018/4/20180423.pdf680childhood glaucomaclassificationEgyptepidemiology |
| spellingShingle | Tharwat H. Mokbel Eman M. El Hefney Sherein M. Hagras Ahmed A. ALNagdy Amani E. Badawi Manal A. Kasem Shereen M. El Shaer Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study International Journal of Ophthalmology 680 childhood glaucoma classification Egypt epidemiology |
| title | Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study |
| title_full | Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study |
| title_fullStr | Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study |
| title_full_unstemmed | Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study |
| title_short | Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study |
| title_sort | childhood glaucoma profile in dakahelia egypt a retrospective study |
| topic | 680 childhood glaucoma classification Egypt epidemiology |
| url | http://www.ijo.cn/en_publish/2018/4/20180423.pdf |
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